Results 61 to 70 of about 234,149 (288)

Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome

open access: yesAdvanced Science, EarlyView.
Pharmacological SUMOylation inhibition (SUMOi) counteracts tumor immune evasion by unmasking an immunogenic HLA‐I peptide and neoepitope repertoire. By restoring HLA‐I ligand availability through increased antigen processing and presentation, enhanced proteasomal cleavage, and modulated TAP1 peptide affinity, SUMOi boosts tumor immunogenicity ...
Uta M. Demel   +19 more
wiley   +1 more source

Alive and kicking: a progress report on Open Access, institutional repositories, and health information [PDF]

open access: yes, 2007
The Open Access movement has promoted two parallel strands of information dissemination - OA publishing, and self-archiving in OA repositories. But while the original focus was peer-reviewed scientific research papers, repositories have extended their ...

core   +1 more source

Incorporating on-site activity involvement and sense of belonging into the Mehrabian-Russell model – The experiential value of cultural tourism destinations [PDF]

open access: yes, 2019
© 2019, Elsevier. The attached document (embargoed until 15/02/2019) is an author produced version of a paper published in TOURISM MANAGEMENT PERSPECTIVES uploaded in accordance with the publisher’s self- archiving policy.
Chen, Annie   +2 more
core   +2 more sources

Modulating Purothionin Accumulation and Signal Peptide Cleavage Fine‐Tunes Wheat Flour Gluten Properties to Improve Cookie‐Making Quality

open access: yesAdvanced Science, EarlyView.
Dual genetic strategies for improving wheat processing quality by regulating purothionin accumulation to modulate gluten quantity and quality. The first strategy involves targeting signal peptide (SP) cleavage sites (e.g., through mutation) to indirectly reduce gluten content, thereby disrupting gluten network formation.
Yijie Liu   +16 more
wiley   +1 more source

Self Archive Initiative

open access: yes, 2007
Ari Friedman's Self Archive Initiative is back online.  The original was a wiki that Ari took down when it ran into technical problems.  The new version is not a wiki, just the get the content back online, but Ari hopes to solve the technical problems one day and restore the wiki.
openaire   +1 more source

The green economy, sustainability transitions and transition regions : a case study of Boston [PDF]

open access: yes, 2014
This paper is focused upon exploring the development of the green economy in particular locations, with the aim of identifying why some cities and regions have been successful in engendering green growth.
Gibbs, David, O'Neill, Kirstie
core   +3 more sources

MGM as a Large‐Scale Pretrained Foundation Model for Microbiome Analyses in Diverse Contexts

open access: yesAdvanced Science, EarlyView.
We present the Microbial General Model (MGM), a transformer‐based foundation model pretrained on over 260,000 microbiome samples. MGM learns contextualized microbial representations via self‐supervised language modeling, enabling robust transfer learning, cross‐regional generalization, keystone taxa discovery, and prompt‐guided generation of realistic,
Haohong Zhang   +5 more
wiley   +1 more source

Repositories for Institutional Open Access: Mandated Deposit Policies

open access: yes, 2006
Only 15% of articles are currently being made Open Access (OA) through spontaneous self-archiving efforts by their authors. They average 25%-250% more citations in all 12 disciplines tested so far.
Brody, Tim   +7 more
core  

HiST: Histological Images Reconstruct Tumor Spatial Transcriptomics via MultiScale Fusion Deep Learning

open access: yesAdvanced Science, EarlyView.
HiST, a multiscale deep learning framework, reconstructs spatially resolved gene expression profiles directly from histological images. It accurately identifies tumor regions, captures intratumoral heterogeneity, and predicts patient prognosis and immunotherapy response.
Wei Li   +8 more
wiley   +1 more source

FLORe – Florence Repository. The University of Florence Open Archive

open access: yesJLIS.it, 2013
The University of Florence has a long and consolidated experience in the exploitation of open archives and self archiving by researchers. After a short introduction on current open access context in Europe and in Italy, the article recalls past ...
Gaia Innocenti   +2 more
doaj   +6 more sources

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