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Self-Assembling Peptides as Immunomodulatory Biomaterials

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
Self-assembling peptides are a type of biomaterial rapidly emerging in the fields of biomedicine and material sciences due to their promise in biocompatibility and effectiveness at controlled release. These self-assembling peptides can form diverse nanostructures in response to molecular interactions, making them versatile materials.
Jeffrey D Hartgerink, Andrea Molina
exaly   +5 more sources
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Self‐Assembly of Tetraphenylalanine Peptides

Chemistry – A European Journal, 2015
AbstractThree different tetraphenylalanine (FFFF) based peptides that differ at the N‐ and C‐termini have been synthesized by using standard procedures to study their ability to form different nanoassemblies under a variety of conditions. The FFFF peptide assembles into nanotubes that show more structural imperfections at the surface than those formed ...
Mayans Tayadella, Enric   +8 more
openaire   +5 more sources

Molecular Modeling of Self-Assembling Peptides

ACS Applied Bio Materials, 2023
Peptide epitopes mediate as many as 40% of protein-protein interactions and fulfill signaling, inhibition, and activation roles within the cell. Beyond protein recognition, some peptides can self- or coassemble into stable hydrogels, making them a readily available source of biomaterials.
Stephen J. Jones, Alberto Perez
openaire   +2 more sources

Peptide Synthesis and Self-Assembly

2011
Peptides and proteins are the most diverse building blocks in biomolecular self-assembly in terms of chemistry, nanostructure formation and functionality. Self-assembly is an intrinsic property of peptides. In this chapter, we attempt to address the following issues: How can we synthesize a self-assembling peptide? What are the fundamental physical and
S, Maude   +6 more
openaire   +2 more sources

Role of peptide self‐assembly in antimicrobial peptides

Journal of Peptide Science, 2015
Antimicrobial peptides (AMPs) are considered as potential antibiotic substitutes because of their potent activities. Previous studies mainly focused on the effects of peptide charges and secondary structures, but the self‐assembly of AMPs was neglected.
Xibo, Tian   +4 more
openaire   +2 more sources

Exploiting biocatalysis in peptide self‐assembly

Peptide Science, 2010
AbstractThis review article covers recent developments in the use of enzyme‐catalyzed reactions to control molecular self‐assembly (SA), an area that merges the advantages of biocatalysis with soft materials self‐assembly. This approach is attractive because it combines biological (chemo‐, regio‐, and enantio‐) selectivity with the versatility of ...
Williams, Richard J.   +2 more
openaire   +4 more sources

Thermodynamics for the Self-Assembly of Alkylated Peptides

Langmuir, 2022
Self-assembling peptides form aggregates with various nanostructures such as spheres, sheets, and fibers and have potential applications in nanomedicine and drug delivery. The alkylation of peptides is a promising strategy for controlling the self-assembly of peptides.
Ai Sato   +3 more
openaire   +2 more sources

Molecular designer self-assembling peptides

Chemical Society Reviews, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Xiaojun, Zhao, Shuguang, Zhang
openaire   +2 more sources

Designer Self‐Assembling Peptide Materials

Macromolecular Bioscience, 2007
Abstract Understanding of macromolecular materials at the molecular level is becoming increasingly important for a new generation of nanomaterials for nanobiotechnology and other disciplines, namely, the design, synthesis, and fabrication of nanodevices at the molecular scale from bottom up.
Xiaojun, Zhao, Shuguang, Zhang
openaire   +2 more sources

Peptide self-assembly: thermodynamics and kinetics

Chemical Society Reviews, 2016
This review is focused on thermodynamic and kinetic contributions to the self-assembly and structural regulation of representative peptide building blocks.
Juan, Wang   +3 more
openaire   +2 more sources

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