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Self-Assembling Peptides as Immunomodulatory Biomaterials
Self-assembling peptides are a type of biomaterial rapidly emerging in the fields of biomedicine and material sciences due to their promise in biocompatibility and effectiveness at controlled release. These self-assembling peptides can form diverse nanostructures in response to molecular interactions, making them versatile materials.
Jeffrey D Hartgerink, Andrea Molina
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Self‐Assembly of Tetraphenylalanine Peptides
Chemistry – A European Journal, 2015AbstractThree different tetraphenylalanine (FFFF) based peptides that differ at the N‐ and C‐termini have been synthesized by using standard procedures to study their ability to form different nanoassemblies under a variety of conditions. The FFFF peptide assembles into nanotubes that show more structural imperfections at the surface than those formed ...
Mayans Tayadella, Enric +8 more
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Molecular Modeling of Self-Assembling Peptides
ACS Applied Bio Materials, 2023Peptide epitopes mediate as many as 40% of protein-protein interactions and fulfill signaling, inhibition, and activation roles within the cell. Beyond protein recognition, some peptides can self- or coassemble into stable hydrogels, making them a readily available source of biomaterials.
Stephen J. Jones, Alberto Perez
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Peptide Synthesis and Self-Assembly
2011Peptides and proteins are the most diverse building blocks in biomolecular self-assembly in terms of chemistry, nanostructure formation and functionality. Self-assembly is an intrinsic property of peptides. In this chapter, we attempt to address the following issues: How can we synthesize a self-assembling peptide? What are the fundamental physical and
S, Maude +6 more
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Role of peptide self‐assembly in antimicrobial peptides
Journal of Peptide Science, 2015Antimicrobial peptides (AMPs) are considered as potential antibiotic substitutes because of their potent activities. Previous studies mainly focused on the effects of peptide charges and secondary structures, but the self‐assembly of AMPs was neglected.
Xibo, Tian +4 more
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Exploiting biocatalysis in peptide self‐assembly
Peptide Science, 2010AbstractThis review article covers recent developments in the use of enzyme‐catalyzed reactions to control molecular self‐assembly (SA), an area that merges the advantages of biocatalysis with soft materials self‐assembly. This approach is attractive because it combines biological (chemo‐, regio‐, and enantio‐) selectivity with the versatility of ...
Williams, Richard J. +2 more
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Thermodynamics for the Self-Assembly of Alkylated Peptides
Langmuir, 2022Self-assembling peptides form aggregates with various nanostructures such as spheres, sheets, and fibers and have potential applications in nanomedicine and drug delivery. The alkylation of peptides is a promising strategy for controlling the self-assembly of peptides.
Ai Sato +3 more
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Molecular designer self-assembling peptides
Chemical Society Reviews, 2006AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Xiaojun, Zhao, Shuguang, Zhang
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Designer Self‐Assembling Peptide Materials
Macromolecular Bioscience, 2007Abstract Understanding of macromolecular materials at the molecular level is becoming increasingly important for a new generation of nanomaterials for nanobiotechnology and other disciplines, namely, the design, synthesis, and fabrication of nanodevices at the molecular scale from bottom up.
Xiaojun, Zhao, Shuguang, Zhang
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Peptide self-assembly: thermodynamics and kinetics
Chemical Society Reviews, 2016This review is focused on thermodynamic and kinetic contributions to the self-assembly and structural regulation of representative peptide building blocks.
Juan, Wang +3 more
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