Results 21 to 30 of about 51,073 (189)

Amyloid Inspired Self-Assembled Peptide Nanofibers [PDF]

Biomacromolecules, 2012
Amyloid peptides are important components in many degenerative diseases as well as in maintaining cellular metabolism. Their unique stable structure provides new insights in developing new materials. Designing bioinspired self-assembling peptides is essential to generate new forms of hierarchical nanostructures.
Cinar G., Ceylan H., Urel, M., Erkal, T.S., Deniz Tekin, E., Tekinay, A.B., Dâna, A., Guler, M.O.   +7 more
openaire   +6 more sources

Peptide Self-Assemblies for Drug Delivery [PDF]

Current Topics in Medicinal Chemistry, 2015
Peptide amphiphiles (PAs) are novel engineered biomaterials able to self-assemble into supramolecular systems that have shown significant promise in drug delivery across the cell membane and across challenging biological barriers showing promise in the field of brain diseases, regenerative medicine and cancer. PAs are amino-acid block co-polymers, with
Moreira Leite, Diana, Barbu, Eugen, Pilkington, Geoffrey John, Lalatsa, Aikaterini   +3 more
openaire   +4 more sources

Self-assembling Venturi-like peptide nanotubes [PDF]

Nanoscale, 2017
We describe the design and synthesis of self-assembling peptide nanotubes that have an internal filter area and whose length and internal diameters, at the entrance and in the constricted area, are precisely controlled.
Fuertes García, Alberto, Ozores, Lionel Haxel, Amorín López, Manuel, Granja Guillán, Juan Ramón   +3 more
openaire   +3 more sources

Biological designer self-assembling peptide nanofiber scaffolds significantly enhance osteoblast proliferation, differentiation and 3-D migration. [PDF]

PLoS ONE, 2007
A class of self-assembling peptide nanofiber scaffolds has been shown to be an excellent biological material for 3-dimension cell culture and stimulating cell migration into the scaffold, as well as for repairing tissue defects in animals. We report here
Akihiro Horii, Xiumei Wang, Fabrizio Gelain, Shuguang Zhang   +3 more
doaj   +1 more source

Alamethicin self-assembling in lipid membranes: concentration dependence from pulsed EPR of spin labels [PDF]

, 2018
The antimicrobial action of the peptide antibiotic alamethicin (Alm) is commonly related to peptide self-assembling resulting in the formation of voltage-dependent channels in bacterial membranes, which induces ion permeation.
De Zotti, Marta, Dzuba, Sergei A, Formaggio, Fernando, Syryamina, Victoria N, Toniolo, Claudio   +4 more
core   +1 more source

Self‐assembling amphiphilic peptides

Journal of Peptide Science, 2014
The self‐assembly of several classes of amphiphilic peptides is reviewed, and selected applications are discussed. We discuss recent work on the self‐assembly of lipopeptides, surfactant‐like peptides and amyloid peptides derived from the amyloid‐βpeptide. The influence of environmental variables such as pH and temperature on aggregate nanostructure is
Dehsorkhi, Ashkan, Castelletto, Valeria, Hamley, Ian W.   +2 more
openaire   +2 more sources

Multicomponent Peptide Hydrogels as an Innovative Platform for Cell-Based Tissue Engineering in the Dental Pulp

Pharmaceutics, 2021
In light of the increasing levels of antibiotic resistance, nanomaterials and novel biologics are urgently required to manage bacterial infections. To date, commercially available self-assembling peptide hydrogels have not been studied extensively for ...
Marina E. Afami, Ikhlas El Karim, Imad About, Anna D. Krasnodembskaya, Garry Laverty, Fionnuala T. Lundy   +5 more
doaj   +1 more source

Self-Assembled Peptide Hydrogels in Regenerative Medicine

Gels, 2023
Regenerative medicine is a complex discipline that is becoming a hot research topic. Skin, bone, and nerve regeneration dominate current treatments in regenerative medicine.
Shuangyang Li, Qixuan Yu, Hongpeng Li, Meiqi Chen, Ye Jin, Da Liu   +5 more
doaj   +1 more source

Ligation of anti-cancer drugs to self-assembling ultrashort peptides by click chemistry for localized therapy [PDF]

, 2013
Self-assembling ultrashort peptides from aliphatic amino acids were functionalized with platinum anti-cancer drugs by click chemistry. Oxaliplatin-derived hybrid peptide hydrogels with up to 40% drug loading were tested for localized breast cancer ...
Chan, Kiat-Hwa, Gopalan, Began, Hauser, Charlotte A. E., Joshi, Mangesh, Lakshmanan, Anupama, Lam, Dang Hoang, Mishra, Archana, Reithofer, Michael R., Wang, Shu   +8 more
core   +1 more source

Self‐Assembly of Tetraphenylalanine Peptides

Chemistry – A European Journal, 2015
AbstractThree different tetraphenylalanine (FFFF) based peptides that differ at the N‐ and C‐termini have been synthesized by using standard procedures to study their ability to form different nanoassemblies under a variety of conditions. The FFFF peptide assembles into nanotubes that show more structural imperfections at the surface than those formed ...
Mayans Tayadella, Enric, Ballano Ballano, María Gema, Casanovas Salas, Jordi, Díaz Andrade, Angélica María, Pérez Madrigal, Maria del Mar, Estrany Coda, Francesc, Puiggalí Bellalta, Jordi, Cativiela Marín, Carlos A., Alemán Llansó, Carlos   +8 more
openaire   +5 more sources