A novel protein purification scheme based on salt inducible self-assembling peptides
Microbial Cell Factories, 2023 Background Protein purification remains a critical need for biosciences and biotechnology. It frequently requires multiple rounds of chromatographic steps that are expensive and time-consuming. Our lab previously reported a cleavable self-aggregating tag
Guang Zeng +5 more
doaj +1 more source
Assessment of Enamel Remineralisation After Treatment with Four Different Remineralising Agents: A Scanning Electron Microscopy (SEM) Study [PDF]
Journal of Clinical and Diagnostic Research, 2017 Introduction: Decades of research has helped to increase our knowledge of dental caries and reduce its prevalence. However, according to World Oral Health report, dental caries still remains a major dental disease.
Renita Soares +3 more
doaj +1 more source
Recent advances in self-assembling peptide matrices as functional coatings for implantable devices
Frontiers in Chemistry, 2022 Nature has evolved numerous supramolecular machineries for modulating various cellular functions. Inspired by the assembly of these sophisticated structures in nature, the controlled assembly of synthetic peptides emerges as a promising approach to ...
Yuan Tian, Lei Lu
doaj +1 more source
Biological designer self-assembling peptide nanofiber scaffolds significantly enhance osteoblast proliferation, differentiation and 3-D migration. [PDF]
PLoS ONE, 2007 A class of self-assembling peptide nanofiber scaffolds has been shown to be an excellent biological material for 3-dimension cell culture and stimulating cell migration into the scaffold, as well as for repairing tissue defects in animals. We report here
Akihiro Horii +3 more
doaj +1 more source
Self-assembling peptide-enriched electrospun polycaprolactone scaffolds promote the h-osteoblast adhesion and modulate differentiation-associated gene expression [PDF]
, 2012 Electrospun polycaprolactone (PCL) is able to support the adhesion and growth of h-osteoblasts and to delay their degradation rate to a greater extent with respect to other polyesters. The drawbacks linked to its employment in regenerative medicine arise
V. Samouillan +23 more
core +1 more source
Self‐assembling amphiphilic peptides
Journal of Peptide Science, 2014 The self‐assembly of several classes of amphiphilic peptides is reviewed, and selected applications are discussed. We discuss recent work on the self‐assembly of lipopeptides, surfactant‐like peptides and amyloid peptides derived from the amyloid‐ β peptide.
Dehsorkhi, Ashkan +2 more
openaire +2 more sources
Pharmaceutics, 2021 In light of the increasing levels of antibiotic resistance, nanomaterials and novel biologics are urgently required to manage bacterial infections. To date, commercially available self-assembling peptide hydrogels have not been studied extensively for ...
Marina E. Afami +5 more
doaj +1 more source
Peptide Self-Assemblies for Drug Delivery [PDF]
Current Topics in Medicinal Chemistry, 2015 Peptide amphiphiles (PAs) are novel engineered biomaterials able to self-assemble into supramolecular systems that have shown significant promise in drug delivery across the cell membane and across challenging biological barriers showing promise in the field of brain diseases, regenerative medicine and cancer. PAs are amino-acid block co-polymers, with
Moreira Leite, Diana +3 more
openaire +4 more sources
Self-Assembled Peptide Hydrogels in Regenerative Medicine
Gels, 2023 Regenerative medicine is a complex discipline that is becoming a hot research topic. Skin, bone, and nerve regeneration dominate current treatments in regenerative medicine.
Shuangyang Li +5 more
doaj +1 more source
Dynamic responsiveness of self‐assembling peptide‐based nano‐drug systems
Interdisciplinary Medicine, 2023 Dynamic‐responsive self‐assembly is the process of ordered supramolecular structure formation or reversible decomposition from building blocks. This process is driven by non‐covalent interactions based on complex stimulus‐responsive systems comprising ...
Yuhan Wang +6 more
doaj +1 more source