Self-assembling peptides as immunomodulatory biomaterials [PDF]
Frontiers in Bioengineering and Biotechnology, 2023 Self-assembling peptides are a type of biomaterial rapidly emerging in the fields of biomedicine and material sciences due to their promise in biocompatibility and effectiveness at controlled release.
Andrea Hernandez +2 more
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Deep Learning Empowers the Discovery of Self‐Assembling Peptides with Over 10 Trillion Sequences [PDF]
Advanced Science, 2023 Self‐assembling of peptides is essential for a variety of biological and medical applications. However, it is challenging to investigate the self‐assembling properties of peptides within the complete sequence space due to the enormous sequence quantities.
Jiaqi Wang +6 more
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Supramolecular Nanomedicines of In-Situ Self-Assembling Peptides [PDF]
Frontiers in Chemistry, 2022 Nanomedicines provide distinct clinical advantages over traditional monomolecular therapeutic and diagnostic agents. Supramolecular nanomedicines made from in-situ self-assembling peptides have emerged as a promising strategy in designing and fabricating
Ying Zhang, Yingying Yu, Jie Gao
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A novel protein purification scheme based on salt inducible self-assembling peptides [PDF]
Microbial Cell Factories, 2023 Background Protein purification remains a critical need for biosciences and biotechnology. It frequently requires multiple rounds of chromatographic steps that are expensive and time-consuming. Our lab previously reported a cleavable self-aggregating tag
Guang Zeng +5 more
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Self-assembling peptides-based nano-cargos for targeted chemotherapy and immunotherapy of tumors: recent developments, challenges, and future perspectives [PDF]
Drug Delivery, 2022 Self-assembling peptides (SAPs) have enormous potential in medical and biological applications, particularly noninvasive tumor therapy. SAPs self-assembly is governed by multiple non-covalent interactions and results in the formation of a variety of ...
Xue-Jun Wang +3 more
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Systematic review of self-assembling peptides as topical agents for treatment and prevention of gastrointestinal bleeding [PDF]
Clinical EndoscopyBackground/Aims Gastrointestinal bleeding is a significant and potentially lethal event. We aimed to review the efficiency and safety of self-assembling peptides for the treatment and prevention of gastrointestinal tract bleeding.
Andrei Voiosu +6 more
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Rapid discovery of self-assembling peptides with one-bead one-compound peptide library [PDF]
Nature Communications, 2021 Self-assembling peptides have a range of potential applications but developing self-assembling sequences can be challenging. Here, the authors report on a one-bead one-compound combinatorial library where fluorescence is used to detect the potential for ...
Pei-Pei Yang +13 more
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Self-Assembling Peptides and Carbon Nanomaterials Join Forces for Innovative Biomedical Applications [PDF]
Molecules, 2021 Self-assembling peptides and carbon nanomaterials have attracted great interest for their respective potential to bring innovation in the biomedical field.
Petr Rozhin +2 more
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De Novo Self-Assembling Peptides Mediate the Conversion of Temozolomide and Delivery of a Model Drug into Glioblastoma Multiforme Cells [PDF]
Biomedicines, 2022 Glioblastoma multiforme (GBM) is the most aggressive central nervous system tumor, and standard treatment, including surgical resection, radiation, and chemotherapy, has not significantly improved patient outcomes over the last 20 years.
Megan Pitz +5 more
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Enhancing the Biological Functionality of Hydrogels Using Self-Assembling Peptides [PDF]
BiomimeticsHydrogels are ECM-mimicking three-dimensional (3D) networks that are widely used in biomedical applications; however, conventional natural and synthetic polymer-based hydrogels present limitations such as poor mechanical strength, limited bioactivity ...
Woo Hyun Kwon +7 more
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