Results 31 to 40 of about 526,180 (352)
Self-assembling prodrugs [PDF]
Chem. Soc. Rev., 2017 Covalent modification of therapeutic compounds is a clinically proven strategy to devise prodrugs with enhanced treatment efficacies. Self-assembly of prodrugs expands the functional space of conventional prodrug design, providing a possible pathway to more effective therapies.
Andrew G. Cheetham +3 more
openaire +3 more sources
Fabrication of Blood Capillary Models for Live Imaging Microarray Analysis
Micromachines, 2020 Conventional microarray analysis usually deals with the monolayer or two-dimensional (2D) assays for the high-throughput screening applications. Even though these cell-based assays are effective for preliminary screening at least to have information on ...
Muhammad Asri Abdul Sisak +4 more
doaj +1 more source
Natural Sciences, 2022 Crystallization of granular assemblies has broad implications for rapid and scalable creation of architected materials with applications ranging from structural materials to microarchitected battery electrodes.
Ivan Grega +3 more
doaj +1 more source
Modeling capsid self-assembly: Design and analysis [PDF]
Phys. Biol. 7 (2010) 045001, 2010 A series of simulations aimed at elucidating the self-assembly dynamics of spherical virus capsids is described. This little-understood phenomenon is a fascinating example of the complex processes that occur in the simplest of organisms. The fact that different viruses adopt similar structural forms is an indication of a common underlying design ...
arxiv +1 more source
Coarse-grained simulation of amphiphilic self-assembly [PDF]
, 2007 We present a computer simulation study of amphiphilic self assembly performed using a computationally efficient single-site model based on Gay-Berne and Lennard-Jones particles. Molecular dynamics simulations of these systems show that free self-assembly
Allen M. P. +5 more
core +1 more source
Nature Communications, 2022 The atomic structure of heterogeneous catalysts is usually a blackbox. Here the authors demonstrate large-scale machine learning atomic simulations help to resolve the catalyst structure and reaction mechanism of encapsulated PtSnO x clusters in zeolite ...
Sicong Ma, Zhi-Pan Liu
doaj +1 more source
Optimized Interactions for Targeted Self-Assembly: Application to Honeycomb Lattice [PDF]
, 2005 We devise an inverse statistical-mechanical methodology to find optimized interaction potentials that lead spontaneously to a target many-particle configuration. Target structures can possess varying degrees of disorder, thus extending the traditional idea of self-assembly to incorporate both amorphous and crystalline structures as well as ...
arxiv +1 more source
The Statistical Mechanics of Dynamic Pathways to Self-assembly
, 2014 We describe some of the important physical characteristics of the `pathways', i.e. dynamical processes, by which molecular, nanoscale and micron-scale self-assembly occurs.
Jack, Robert L., Whitelam, Stephen
core +1 more source
Freezing-induced self-assembly of amphiphilic molecules [PDF]
, 2017 The self-assembly of amphiphilic molecules usually takes place in a liquid phase, near room temperature. Here, using small angle X-ray scattering (SAXS) experiments performed in real time, we show that freezing of aqueous solutions of copolymer ...
Albouy, P. A. +8 more
core +1 more source
Self-assembly of self-assembled molecular triangles
Journal of Chemical Sciences, 2014 A rare variety of self-assembled molecular triangle [Pd3(bpy)3(imidazolate)3](NO3)3, 1 is prepared by the combination of Pd(bpy)(NO3)2 with imidazole, at 1:1 ratio, in acetonitrile-water. Deprotonation of imidazole happened during the course of the complexation reaction where upon the metallomacrocycle is formed. The bowl-shaped trinuclear architecture
Venkatachalam Ramkumar +2 more
openaire +3 more sources