Results 41 to 50 of about 307,894 (242)

Mechanism assay of interaction between blood vessels-near infrared probe and cell surface marker proteins of endothelial cells

Materials Today Bio, 2022
In vivo blood vessels imaging is crucial to study blood vessels related diseases in real-time. For this purpose, fluorescent based imaging is one of the utmost techniques for imaging a living system. The discovery of a new near-infrared probe (CyA-B2) by
Muhammad Asri Abdul Sisak, Fiona Louis, Tomoyuki Miyao, Sun Hyeok Lee, Young-Tae Chang, Michiya Matsusaki   +5 more
doaj   +1 more source

Self-assembly via microfluidics

Lab on a Chip, 2015
Microfluidic techniques provide an intriguing method to control kinetic aspects of the self-assembly of molecular amphiphiles by the facile adjustment of the hydrodynamics of the fluids.
Lei Wang, Samuel Sánchez
openaire   +4 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Creating amphiphilic porosity in two-dimensional covalent organic frameworks via steric-hindrance-mediated precision hydrophilic-hydrophobic microphase separation

Nature Communications
Creating different pore environments within a covalent organic framework (COF) will lead to useful multicompartment structure and multiple functions, which however has been scarcely achieved.
Shu-Yan Jiang, Zhi-Bei Zhou, Shi-Xian Gan, Ya Lu, Chao Liu, Qiao-Yan Qi, Jin Yao, Xin Zhao   +7 more
doaj   +1 more source

DNA-guided self-assembly in living cells

iScience, 2023
Summary: Self-assembly processes exist widely in life systems and play essential roles in maintaining life activities. It is promising to explore the molecular fundamentals and mechanisms of life systems through artificially constructing self-assembly ...
Jinqiao Liu, Jianpu Tang, Zhaobin Tong, Guangshuai Teng, Dayong Yang   +4 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

In situ supramolecular self-assembly for alleviating multidrug resistance in cancer

Supramolecular Materials, 2023
Drug resistance is one of the major causes of cancer treatment failures. In recent years, to combat the issue of drug resistance, a large volume of strategies has been established along the development of biomedical nanomaterials.
Jie Zhao, Xiaobo Wu, Jiali Chen, Chengling Wu, Ruijia Zhang, Qingxin Yao, Jianjun Xie, Yuan Gao   +7 more
doaj   +1 more source

Self-assembly of self-assembled molecular triangles

Journal of Chemical Sciences, 2014
A rare variety of self-assembled molecular triangle [Pd3(bpy)3(imidazolate)3](NO3)3, 1 is prepared by the combination of Pd(bpy)(NO3)2 with imidazole, at 1:1 ratio, in acetonitrile-water. Deprotonation of imidazole happened during the course of the complexation reaction where upon the metallomacrocycle is formed. The bowl-shaped trinuclear architecture
MILI C NARANTHATTA, V RAMKUMAR, DILLIP KUMAR CHAND   +2 more
openaire   +2 more sources

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

OrthoID: profiling dynamic proteomes through time and space using mutually orthogonal chemical tools

Nature Communications
Identifying proteins at organelle contact sites, such as mitochondria-associated endoplasmic reticulum membranes (MAM), is essential for understanding vital cellular processes, yet challenging due to their dynamic nature.
Ara Lee, Gihyun Sung, Sanghee Shin, Song-Yi Lee, Jaehwan Sim, Truong Thi My Nhung, Tran Diem Nghi, Sang Ki Park, Ponnusamy Pon Sathieshkumar, Imkyeung Kang, Ji Young Mun, Jong-Seo Kim, Hyun-Woo Rhee, Kyeng Min Park, Kimoon Kim   +14 more
doaj   +1 more source