Results 21 to 30 of about 1,565,438 (264)

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

A scoping review of UK local government workplace health and wellbeing programmes

BMC Public Health
Background Workplace settings are linked to staff health and wellbeing, affecting sickness absence, presenteeism and productivity. With the growing prevalence of health issues among employees in the UK, including stress and long-term conditions ...
Austen El-Osta, Sami Altalib, Aos Alaa, Mahmoud Al-Ammouri, Manisha Karki, Eva Riboli-Sasco, Azeem Majeed, Laura Kudrna   +7 more
doaj   +1 more source

What is the interplay between self-care confidence, professional support and health literacy among UK adults? A cross-sectional online survey study

BMJ Open
Background The WHO defines self-care as ‘the ability of individuals, families and communities to promote health, prevent disease, maintain health and cope with illness and disability with or without the support of a healthcare provider’, while self-care ...
Peter Smith, Austen El-Osta, Sami Altalib, Mahmoud Al Ammouri   +3 more
doaj   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source

Dietary Protein Intake and Peritoneal Protein Losses in Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) patients lose protein in their waste dialysate, potentially increasing their risk for malnutrition. We wished to determine whether there was any association between losses and dietary protein intake (DPI). Methods DPI was assessed from 24‐h dietary recall using Nutrics software.
Haalah Shaaker, Andrew Davenport
wiley   +1 more source

Components of joint health and wellbeing strategies: a pan-London review of all 33 local authorities

BMC Public Health
Background In the UK, Health and Wellbeing Strategies (JHWS) were introduced to identify and help address the health needs of local communities. JHWS translate a borough’s Joint Strategic Needs assessment into actionable outcomes and prioritises areas of
Marie Line El Asmar, Manisha Karki, Bathsheba Mall, Eva Riboli-Sasco, Austen El-Osta   +4 more
doaj   +1 more source

Embedding work coaches in GP practices: Findings from an interview-based study in the UK

Public Health in Practice
Background: The integration of work coaches (WCs) and disability employment advisors (DEAs) into General Practitioner (GP) practices in the UK aims to address the interplay between health and employment by facilitating access to employment support ...
Shriti Pattani, Marie Line El Asmar, Manisha Karki, Eva Riboli Sasco, Lara Shemtob, Kabir Varghese, Austen El-Osta   +6 more
doaj   +1 more source

The effects of living environment on disaster workers: a one–year longitudinal study

BMC Psychiatry, 2016
Background Defense Force workers engaged in disaster relief activities might suffer from strong psychological stress due to the tasks that they had been involved.
Masanori Nagamine, Nahoko Harada, Jun Shigemura, Kosuke Dobashi, Makiko Yoshiga, Naoki Esaki, Miyuki Tanaka, Masaaki Tanichi, Aihide Yoshino, Kunio Shimizu   +9 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Investigating facilitators and barriers to the routine provision of HIV PrEP in community pharmacies in London

BMC Health Services Research
Background The United Kingdom’s (UK) integration of Pre-exposure Prophylaxis (PrEP) into community pharmacies presents an alternative avenue for supporting Human Immunodeficiency Virus (HIV) prevention.
Marsha Alter, Shivali Lakhani, Aos Alaa, Manisha Karki, Eva Riboli-Sasco, Austen El-Osta   +5 more
doaj   +1 more source