Results 31 to 40 of about 1,565,438 (264)
BMJ OpenObjectives This study examines awareness, perceived legitimacy, trust and readiness for the implementation of lifestyle medicine within National Health Service (NHS) prevention pathways among community-dwelling adults and healthcare professionals (HCPs ...
Azeem Majeed +4 more
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CARE OF THE SELF AS LIMIT-EXPERIENCE
Вісник Харківського національного університету імені В.Н. Каразіна. Серия: Теорія культури та філософіі науки, 2021 In the article there was made the analysis of Foucault’s concept of experience within contemporary anthropological crisis. It was emphasised that European humankind and culture have got hazardously growing distance between knowledge (truth) and human’s ...
Olha Mykolayivna Horodyska
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Frontiers in Pain Research, 2021 This brief report details a pilot analysis conducted to explore racial differences in pain sensitivity and unpleasantness between cognitively healthy Black and White adults, stratified by sex.
Karen O. Moss +17 more
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
BMC Health Services ResearchBackground Despite advancements in HIV prevention, barriers and disparities in accessing Pre-exposure Prophylaxis (PrEP) from specialist services persist.
Aos Alaa +4 more
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Clinical Journal of Oncology Nursing, 2019 Poor provider health and clinical staff burnout remain a threat to quality patient care. A meta-analysis of studies about nurse burnout reported the following estimates about nurses in clinical practice: 31% had high emotional exhaustion, 24% demonstrated high depersonalization, and 38% had low personal accomplishment.
openaire +3 more sources
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source