Results 71 to 80 of about 1,790,901 (338)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Mirror therapy and self-care autonomy after stroke: an intervention program [PDF]

, 2018
Background: In patients with middle cerebral artery (MCA) stroke, changes in upper limb function lead to dependence on others for self-care. In the process of recovering autonomy/independence, there is evidence on the effectiveness of sensory stimulation
Castro, Pedro, Couto, Glória, Martins, Maria, Reis, Maria   +3 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and kinematic gait characteristics in older patients with type 2 diabetes mellitus with and without sarcopenia

Scientific Reports
To investigate the differences in gait characteristics between older patients with type 2 diabetes with and without sarcopenia, using a three-dimensional motion analysis system.
Tomotaka Manabe, Wakako Tsuchida, Toshihiro Kobayashi, Masahiro Fujimoto, Takuma Inai, Kohei Kido, Shoma Kudo, Kensaku Fukunaga, Takanobu Saheki, Takafumi Yoshimura, Hitomi Imachi, Koji Murao   +11 more
doaj   +1 more source

Depression in Chinese patients with type 2 diabetes: associations with hyperglycemia, hypoglycemia, and poor treatment adherence. [PDF]

, 2015
BackgroundWe hypothesize that depression in type 2 diabetes might be associated with poor glycemic control, in part due to suboptimal self-care. We tested this hypothesis by examining the associations of depression with clinical and laboratory findings ...
Chan, Juliana Cn, China Depression in Chinese Patients with Type 2 Diabetes (DD2) Study Group, Guo, Xiaohui, Ji, Linong, Jia, Weiping, Kong, Alice Ps, Li, Wenhui, Luk, Andrea Oy, Morisky, Donald E, Oldenburg, Brian, Sartorius, Norman, Ting, Rose Zw, Weng, Jianping, Wing, Yun-Kwok, Yang, Wenying, Zhang, Yuying   +15 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

BU Libraries self-care "Take a coloring break" posters [PDF]

, 2019
These posters were created to encourage self-care and healthy habits during exam periods at ...
Manin, Haley
core  

Modeling Participant Toward Self-care Deficit on Schizophrenic Clients [PDF]

, 2017
Introduction: Scizophrenia is a disease which affect of brain, causing impaired perception, thought, emotion, movement, and behavior, such as self care deficit. Self-care deficit is an impaired ability to bathing, dressing, eating and toileting. Modeling
Kurniawan, K. E. (Krisna), Nihayati, H. E. (Hanik), Yusuf, A. (Ah)   +2 more
core   +2 more sources