Results 81 to 90 of about 9,713,535 (260)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Self-care for health in rural Bangladesh [PDF]

An interest in human coping applicable to endemic disease environments such as Bangladesh now includes disease mitigation and management through self-care.
Edgeworth, Ross
core  

Drivers and barriers to promoting self-care in individuals living with multiple long-term health conditions: a cross-sectional online survey of health and care professionals

BMC Public Health
Background Self-care is an important part of preventing unwarranted decline in poor health linked to multimorbidity and in maintaining or improving health. Health and social care professionals provide support for self-care, which can positively influence
Susan Barber, Benedict Hayhoe, Sonia Richardson, John Norton, Manisha Karki, Austen El-Osta   +5 more
doaj   +1 more source

FROM SELF-CARE TO COLLECTIVE CARE

Sur: International Journal on Human Rights, 2020
Human Rights Defenders (HRDs) across the world report a common experience of closing space for opposition to oppressive repositories of power, whether at the hand of government or the private sector. One of the strategies of resistance developed by HRDs
Lisa Chamberlain
doaj  

Care and the self

Medicine Anthropology Theory, 2021
N ...
Lauren Wynne
doaj  

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Young people's participation in the development of a self-care intervention--a multi-site formative research study. [PDF]

, 2013
The poor outcomes of young people with chronic health conditions indicate that current services and self-care programmes are not meeting the needs of young people.
Kime, N, Webster, L, McKenna, J
core   +1 more source

Acute Onset of Suicidal Ideation after Starting Lemborexant in a Patient with a Mood Disorder

Sleep Science
A 24-year-old woman with treatment-resistant depressive symptoms and chronic insomnia developed acute, intrusive suicidal ideation with intent on day 5 after starting lemborexant 10 mg nightly.
Renato Rodrigo Silva, Marjorie Mastellaro Baruzzi, Bianca Besteti Fernandes Damiano, Rodolfo Furlan Damiano   +3 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Developing self-care at work [PDF]

Phd Title: Developing self-care at workABSTRACTThis PhD Study explored the practical development of self-care at work. The study enabled an understanding of self-care at work as a phenomena, and enabled the practitioners involved to free themselves from ...
Keep, Jane A
core