Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
‘It's like the bad guy in a movie who just doesn't die’ : a qualitative exploration of young people's adaptation to eczema and implications for self‐care [PDF]
, 2019 Background Eczema is a common childhood inflammatory skin condition, affecting more than one in five children. A popular perception is that children ‘outgrow eczema’, although epidemiological studies have shown that, for many, eczema follows a lifelong ...
Ghio, D +6 more
core +3 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Role of community pharmacists in patients' self-care and self-medication [PDF]
, 2015 This review highlights the growing prominence of self-care and explores the contribution of community pharmacy. Firstly, background to self-care is discussed, followed by placing self-care in context with regard to the general public and accessing ...
Rutter, Paul
core +2 more sources
Cancer MedicineContext Bodily pain and cognitive concerns are both prevalent and share similar underlying mechanisms. A few studies have suggested that pain and cognitive concerns may be linked through substance use coping; however, this relationship remains unclear ...
Yesol Yang +3 more
doaj +1 more source
FROM SELF-CARE TO COLLECTIVE CARE
Sur: International Journal on Human Rights, 2020 Human Rights Defenders (HRDs) across the world report a common experience of closing space for opposition to oppressive repositories of power, whether at the hand of government or the private sector. One of the strategies of resistance developed by HRDs
Lisa Chamberlain
doaj
Self care in patients with chronic heart failure. Pilot study - self care includes problems
Biomedical Papers, 2015 Aim: The goal of this pilot study was to define the scope of therapeutic self-care demand in heart failure (HF) patients according to the concepts of self-care postulated by D.E.
Renata Halmo +3 more
doaj +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Informing the development of services supporting self-care for long term mental health conditions: A mixed method study of community based mental health initiatives in England [PDF]
, 2012 Background Supporting self-care is being explored across health care systems internationally as an approach to improving care for long term conditions in the context of ageing populations and economic constraint.
Adams, K +9 more
core +2 more sources
BMC Public HealthBackground Self-care is an important part of preventing unwarranted decline in poor health linked to multimorbidity and in maintaining or improving health. Health and social care professionals provide support for self-care, which can positively influence
Susan Barber +5 more
doaj +1 more source