Results 81 to 90 of about 1,790,901 (338)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Health coaching for people with long-term conditions and multimorbidity: a mixed methods prospective service evaluation of Structured Agenda-free Coaching Conversations (StACC) in UK primary care

BMC Public Health
Background Enhanced patient engagement has been linked to health service sustainability. The Structured Agenda-free Coaching Conversation (StACC) model aims to support people with one or more long-term conditions through a strengths-based approach ...
Kate Henry, Austen El-Osta, Kathleen Leedham-Green   +2 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Using context mapping for planning implementation of movement behavior change in physiotherapy

BMC Health Services Research
Background Physiotherapists often lack a comprehensive understanding of self-management and encounter challenges in providing self-management support. The Keep Moving Support Tool (KMST) was developed to support physiotherapists in their role as health ...
Sofie van Rongen, Joan M. Dallinga, Anita Feleus, Ingrid Rosbergen, Alice Schut, Myrenka Bik, Petra Siemonsma, Sanne I. de Vries, Arlette E. Hesselink   +8 more
doaj   +1 more source

Factors Affecting Self-Care Ability among Children with Mental Retardation [PDF]

, 2018
Background: Mental retardation is a developmental problem manifested during a child’s years of development (i.e. 0-18 years old). It is a condition whereby a child’s intelligence and adaptability are significantly below the average level of his peers ...
Indanah, I. (Indanah)
core  

Developing a stoma acceptance questionnaire to improve motivation to adhere to enterostoma self-care [PDF]

, 2017
IntroductionIn stoma care, patient education is often weak in terms of improving patientsâ level of acceptance of living with a stoma. Self-care educational interventions in enterostomal patients, which according to Oremâs Theory should take into account
Aleo, Giuseppe, Bagnasco, Annamaria, Catania Gianluca, Sasso, Loredana, Watson, Roger, Zanini, Milko   +5 more
core   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Effect of Intervention Program on Self Care Skills and Self-efficacy among Patients with Depression [PDF]

, 2022
Amal Mohamed Osama, Amal Ibrahim Sabra, Mona Mohamed Barakat   +2 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source