Effect of Loading Rate and Initial Strain on Seismic Performance of an Innovative Self-Centering SMA Brace. [PDF]
Jia Y +5 more
europepmc +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
The Seismic Performance of New Self-Centering Beam-Column Joints of Conventional Island Main Buildings in Nuclear Power Plants. [PDF]
Pei Q, Wu C, Cheng Z, Ding Y, Guo H.
europepmc +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Utilizing a new self-centering hysteresis model to assess the seismic vulnerability of a long-span cable-stayed bridge equipped with SMA wire-based roller bearings. [PDF]
Li S, Farshad HD, Wang JQ, Alam MS.
europepmc +1 more source
Sustainable bioplastics manufacturing from renewable sources
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto +6 more
wiley +1 more source
SMA-Activated Double-Stage Yielding BRB: Experimental and FEM Insights
To address the limitations of traditional buckling-restrained braces (BRB), which feature a single-stage yielding and inadequate energy dissipation under small earthquakes, this study proposes a novel double-stage yielding buckling-restrained brace (DSY ...
Huijie Huang +4 more
doaj +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
This paper presented the development process of a novel multi-layer self-centering damper utilizing a NiTi shape memory alloy (SMA) with remarkable superelastic properties.
Hua Zhang +3 more
doaj +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source

