Results 231 to 240 of about 86,624 (285)

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

A scoping review of workplace violence against healthcare workers in Singapore. [PDF]

Front Public Health
Sing P, Lau ACH.
europepmc   +1 more source

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

Advanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang, Xinyu Qu, Tingting Ren, Tong Wu, Weiyong Gu, Jingxin Ding, Keqin Hua, Junjun Qiu   +7 more
wiley   +1 more source

Yeast-Secreted Protein PgSCP and Citrus Transcription Factor CsMIKC Synergize to Activate Green Mould Resistance in Fruit. [PDF]

Mol Plant Pathol
Chen O, Huang R, Xu Y, Wang W, Ming J, Zeng K.   +5 more
europepmc   +1 more source

Photocatalytically Activated Cu‐N1S3 Single‐Atom Nanozyme: Enhancing Enzyme Activities and Antibacterial Synergy for Highly Efficient Fruit Preservation

Advanced Science, EarlyView.
This study presents S‐coordinated Cu single‐atom nanozymes (Cu/CNS) fabricated via mild photocatalytic self‐assembly strategy. The nanozyme exhibits exceptional multi‐enzyme activity and near‐perfect antimicrobial efficacy. Incorporated into chitosan‐gelatin film, it enables pH‐responsive, broad‐spectrum fruit preservation, more than doubling the shelf‐
Chuanlong Men, Chenchen Wu, Lei Wang, Shengjie Gao, Yu Mao, Wei Liu, Changhong Liu, Lei Zheng   +7 more
wiley   +1 more source

A Comparative Multicenter Cross-Sectional Study on Hypoglycemia in Young Adults and Older Adults With Type 2 Diabetes Mellitus in an Outpatient Setting in Sri Lanka. [PDF]

J Diabetes Res
Jayasekera PT, Senaratne T, Lamabadusuriya D, Sathischandra H, Matthias AT, Jayasekera P, Herath M, De Zoysa WD, Senaratne G, Pathirage M, Jayasinghe K, Karunaratne S, Sudarshan P, Sujanitha V, Rajaratnam N, Wickramaratne D, Umakanth M, Ratnayake B, Rasnayake L, Liyanage R, Pushpakumara J, Wanigarathne T, Siriwardhane P, Kumara YU, Kuruppu S, Edirisinghe D, Wijesinghe N.   +26 more
europepmc   +1 more source

TOGR3, a Proteasome β4 Subunit, Orchestrates Sugar Homeostasis to Trade Off Growth and Thermotolerance in Rice

Advanced Science, EarlyView.
This study identifies a novel thermoregulatory mechanism in rice: TOGR3 partners with 26S proteasome subunits, including TT1, to drive thermoresponsive ubiquitin–proteasome activity, maintaining sugar homeostasis in stomatal regulation to balance growth and stress resistance.
Biyao Zhang, Xiaoyan Wu, Ting Xu, Feifei Guo, Xiaolu Shen, Cuiping Meng, Yanan Wang, Xue Han, Hong Zhao, Yongbiao Xue   +9 more
wiley   +1 more source

The Invisible Lens: Why Theoretical Models Are Essential for Interpreting Immune Phenomena. [PDF]

Scand J Immunol
Manjili MH.
europepmc   +1 more source

Populist politics and liberal democracy in Central and Eastern Europe [PDF]

, 2008
Gyarfasova, Olga, Meseznikov, Grigorij, Smilov, Daniel   +2 more
core  

Thyrotoxic Hypokalemic Periodic Paralysis: Pathophysiological Mechanisms. [PDF]

Endocrinol Metab (Seoul)
Qing G, Zakaria WNA, Rom FZM, Nik WNFHW, Zulkeflee HA, Rahim SNA.   +5 more
europepmc   +1 more source