Results 31 to 40 of about 86,624 (285)

SELF-DEFENCE IN SPECIAL SITUATIONS (I) [PDF]

Challenges of the Knowledge Society, 2015
In the reality of practical cases and in certain special situations, self-defence may present some complex forms consisting either in accidental amplification of the issue in fact when self-defence is claimed, or in the correlation in fact of self ...
Lamya-Diana HĂRĂTĂU
doaj  

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

The Right to Defence in Criminal Proceedings: International Law Aspects

Teisė, 2022
The article deals with the right to defence in criminal proceedings in accordance with international law norms. It is proved that ensuring the right to defence is one of the basic principles of criminal justice and is a prerequisite for the achievement ...
Vitalii Gutnyk
doaj   +1 more source

Bodily Limits to Autonomy: Emotion, Attitude, and Self-Defence [PDF]

, 2009
Many of us took pride in never feeling violent, never hitting. We had not thought deeply about our relationships to inflicting physical pain. Some of us expressed terror and awe when confronted with physical strength on the part of others.
Burrow, Sylvia
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Defending against environmental threats: Unveiling household adaptation strategies and population heterogeneity

Environment International
Humanity faces a variety of risks from pollution and environmental degradation. Societal advancement has equipped the public with numerous self-protection measures to mitigate these threats.
Chenyi Du, Wenling Liu
doaj   +1 more source

Hätävarjelun ja hätävarjelun liioittelun rajat [PDF]

, 2017
Tässä opinnäytetyössä käsiteltiin hätävarjelua ja hätävarjelun liioittelua sekä niiden välisiä rajoja. Tavoitteena oli selvittää, mitä edellytyksiä kuuluu hätävarjeluun ja hätävarjelun liioitteluun sekä missä menee näiden raja ja mitkä asiat ovat ...
Tolonen, Sarita
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Self-Defence as a Circumstance Precluding the Wrongfulness of the Use of Force

Utrecht Law Review, 2015
Roberto Ago, the International Law Commission’s second Special Rapporteur on the topic of state responsibility for internationally wrongful acts, defined self-defence as a faculté of a state to use force in response to an act of another state through ...
Cliff Farhang
doaj   +1 more source