Results 121 to 130 of about 7,385,969 (371)
The Tragedy and Promise of Self-Determination [PDF]
, 2020 The principle of self-determination, like Janus, has two faces: negative and positive. Often understood as enabling the fracture of states into national components, the principle is better seen as facilitating the creation of multinational frameworks ...
Slattery, Brian
core
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Learning to Learn and Teaching to Learn
MedEdPublish, 2016 Medical training is notoriously difficult, and the motivation to learn and teach can decline with time. Building from the principles of self-determination theory, we provide reflections of a trainee, a trainee and supervisor, and a faculty supervisor on ...
Jia Zhu, Daniel J. Schumacher
doaj
Territorial Claims as a Limitation to the Right of Self-Determination in the Context of the Falkland Islands Dispute [PDF]
, 1982 This Note will trace the development and present status of the right to self-determination under international law and its applicability to the decolonization of the Falkland Islands.
Schwed, Alejandro
core +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
The Globality of Islam: Sharia as a Nigerian 'Self-Determination' Movement [PDF]
This paper was produced as part of a project at the University of California, Santa Cruz titled Globalization, State Capacity and Islamic Movements. The objective of this paper to assess how globalization and Islam impact the capacity of national states ...
Paul Lubeck, Ronnie Lipschutz and Erik Weeks
core
FEBS Open Bio, EarlyView.Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah +8 more
wiley +1 more source
Corrigendum: Quality of the Physical Education Teacher's Instruction in the Perspective of Self-Determination [PDF]
, 2021 Argenis P. Vergara-Torres +5 more
openalex +1 more source