Results 71 to 80 of about 756,390 (306)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The Problem of Determinism - Freedom as Self-Determination [PDF]

, 2010
There are arguments for determinism. Admittedly, this is opposed by the fact of everyday experience of autonomy. In the following, it is argued for the compatibility of determinism and autonomy.
Wandschneider, Dieter
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Self-determined or non-self-determined? Exploring consumer motivation for sustainable food choices

Sustainable Production and Consumption
Agricultural production is one of the major sources of greenhouse gas emissions with livestock farming accounting for half of the mitigation potential of greenhouse gas emissions of agriculture, forestry, and land-use sectors. Hence, a sustainable transition of the agricultural sector is urgently needed to achieve the objectives outlined in the Paris ...
Schulze, Maureen, Janssen, Meike
openaire   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

THE OPPORTUNITIES OF INTERNET ENVIRONMENT OF CYBERSPACE FOR PERSONAL SELF-DETERMINATION OF YOUTH

Sovremennye Issledovaniâ Socialʹnyh Problem, 2017
The study was conducted in the context of personal self-determination of youth in the process of cybersocialization, which proceeds under influence and as a result of the using of modern Information-communication technologies. And this problem is the one
Tatiana Valentinovna Obidina
doaj   +1 more source

On psychological growth and vulnerability: basic psychological need satisfaction and need frustration as an unifying principle [PDF]

, 2013
Humans have a potential for growth, integration, and well-being, while also being vulnerable to defensiveness, aggression, and ill-being. Self-determination theory (R. M. Ryan & E. L.
Ryan, Richard, Vansteenkiste, Maarten
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Conjuring up the correspondence of high-school students’ self-determination and classroom climate with reading achievement

English Language Teaching Educational Journal, 2020
A prevalent goal of education in schools is reading comprehension enhancement. Therefore, a critical issue in   educational psychology is investigating the factors contributing to increase the reading achievement including both classroom climate and ...
Shahrbanoo Joulide, Akram Faravani, Ali Akbar Boori   +2 more
doaj   +1 more source