Results 81 to 90 of about 6,332,646 (291)

Self-determination in dependence

open access: yesMedicine Anthropology Theory, 2016
n ...
Klaas Willem van der Veen
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

LEGAL ASPECTS OF SELF-DETERMINATION AS REGULATED IN INTERNATIONAL DOCUMENTS

open access: yesIustinianus Primus Law Review
This article examines the historical and political evolution of the right to self-determination, which began as a political slogan used by great powers to annex territories to support their spheres of influence, which gradually developed into a ...
Marija Mirceska
doaj  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

A "New" Strategy for Afghanistan and Its Region

open access: yes, 2009
The report assesses the strategy of the Obama Administration as stated in early 2009 toward Afghanistan and provides recommendations for Afghanistan and its region. This strategy resembles a strategic framework more than a specific strategy.
Liechtenstein Institute on Self-Determination
core  

Motivation for and Challenges in Teacher Research in Underdeveloped Areas of Northwest China: An Exploratory Study

open access: yesBehavioral Sciences
This study explored the motivations and challenges vocational teachers (VTs) face in conducting research in underdeveloped regions of Northwest China.
Na Zhou   +5 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Using a Transition Curriculum to Increase Self-Determination in Transition-Aged Private School Students with Disabilities [PDF]

open access: yes, 2018
The Individuals with Disabilities Education Act (2004) mandates that students with disabilities who attend public schools should have a well-developed transition plan as part of the Individualized Education Plan (IEP) by the time the child is 16 years ...
Lyons, Kylie R.
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

State Building and Security in Afghanistan and the Region

open access: yes, 2003
Recommendations in this report focus on state building and pressing security concerns in Afghanistan and the region. They address the urgent need for establishing security and building of state and society which are closely interconnected, and note that ...
Liechtenstein Institute on Self-Determination
core  

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