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National Open Disclosure Steering Committee Terms of Reference 2022
The HSE National Open Disclosure Steering Committee (ODSC) was established in April 2019, to strengthen corporate oversight, strategic leadership and accountability with the on-going implementation of the National Open Disclosure programme and policy*. (
HSE, National Open Disclosure Steering Committee
core
Penelitian ini adalah penelitian kuantitatif yang bertujuan untuk menguji dan mendapatkan data secara empiris mengenai hubungan intimate friendship dengan self disclosure pada mahasiswa pengguna media sosial Facebook di Fakultas Psikologi Universitas ...
Fiona Almira Pohan +1 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Pilots and athletes: Different concerns, similar concussion non-disclosure.
ObjectivesConcussion non-disclosure research has focused almost exclusively on athletes. The focus on athletic populations has been sensible considering athletes' demonstrated susceptibility to sustaining and concealing concussions.
Craig A Foster +2 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Talking therapies rely on the client being able to reveal their inner feelings and thoughts; however, some people find this type of disclosure very difficult.
McEwan, Kirsten +2 more
core +1 more source
Background Self-regulation of payment disclosure by pharmaceutical industry trade groups is a major global approach to increasing transparency of financial relationships between drug companies and healthcare professionals and organisations. Nevertheless,
Piotr Ozieranski +4 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source

