Results 61 to 70 of about 296,311 (247)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Hubungan Antara Pengungkapan-Diri dan Kepuasan Pernikahan dengan Dimediasi oleh Intimasi

open access: yesPsikologika: Jurnal Pemikiran dan Penelitian Psikologi, 2017
The present study was aimed to examine the relationship between self-disclosure and marital satisfaction, and whether the relation between self-disclosure and marital satisfaction meditated by intimacy.
Arif Romdhon, Hepy Wahyuningsih
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

HUBUNGAN ANTARA SELF DISCLOSURE DENGAN KECEMASAN MENGHADAPI PENSIUN PADA PEGAWAI PT. PLN (PERSERO) WILAYAH SEMARANG

open access: yesJurnal Empati, 2017
Penelitian ini bertujuan untuk mengetahui hubungan antara self disclosure dengan kecemasan menghadapi pensiun pada pegawai PT. PLN (Persero) Wilayah Semarang. Subjek penelitian adalah 75 pegawai yang berusia 51 hingga 55 tahun di PT.
Chanya Paripurastu Sasongko   +1 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

An Experimental Test of Processes Underlying Self-Disclosure in Computer-Mediated Communication

open access: yesCyberpsychology: Journal of Psychosocial Research on Cyberpspace, 2009
A consistent finding in computer-mediated communication (CMC) and Internet research is that, compared to face-to-face communication, CMC results in higher levels of self-disclosure.
Alexander P. Schouten   +2 more
doaj  

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Why We Disclose on Social Media? Towards a Dual-Pathway Model

open access: yesBehavioral Sciences
Grounded in social penetration theory and social capital theory, this study aims to investigate how social media self-disclosure influences bridging and bonding online social capital, and how these in turn affect users’ loneliness and online ...
Qiyu Bai, Qi Dan, Yumin Choi, Siyang Luo
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

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