Results 81 to 90 of about 330,215 (300)

Self-harm in a primary care cohort of older people: incidence, clinical management, and risk of suicide and other causes of death [PDF]

open access: yes, 2018
BACKGROUND: Self-harm is a major risk factor for suicide, with older adults (older than 65 years) having reportedly greater suicidal intent than any other age group.
Ashcroft, DM   +6 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1556-1590, June 2026.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Self-harm following release from incarceration: Patterns and measurement issues

open access: yesInternational Journal of Population Data Science, 2018
Introduction Despite an elevated prevalence of self-harm in the incarcerated adult population, little is known about patterns of self-harm following release from prison.
Rohan Borschmann   +3 more
doaj   +1 more source

Why do adolescents self-harm? An investigation of motives in a community sample [PDF]

open access: yes, 2016
Given the high rates of self-harm among adolescents, recent research has focussed on a better understanding of the motives for the behaviour. The present study had three aims: to investigate (i) which motives are most frequently endorsed by adolescents ...
Hawton, Keith   +3 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

LGBTQIAP+ University Students and Likelihood of Self-Harm [PDF]

open access: yes, 2018
Self-harm is defined as the direct, deliberate destruction or alteration of body tissue (Bakken and Gunter 2012). This research is important because previous research has found that university students are likely to engage in self-harm and that it is an ...
Smith, Evan
core   +2 more sources

"It's a safe space": Self-harm self-help groups [PDF]

open access: yes, 2018
Purpose: The purpose of this paper is to present a qualitative analysis of the role of self-harm self-help groups from the perspective of group members.
Boyce, Melanie J.   +2 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Prevalence and risk factors for repetition of non-fatal self-harm in Hong Kong, 2002–2016: A population-based cohort study

open access: yesThe Lancet Regional Health. Western Pacific, 2020
Background: A history of self-harm is strongly associated with future self-harm attempts. Large-scale Asian cohort studies examining risk factors for repeated self-harm are lacking. This paper reports on annual prevalence, cumulative risk, annual risk of
Yi Chai, Hao Luo, Paul S.F. Yip
doaj   +1 more source

The Link Between Dissociation, Eating Disorders, and Self-Harm [PDF]

open access: yes, 2014
Many researchers and psychological professionals believe that there is a link between eating disorders and self-harm, though this has been less widely researched than other correlations such as that between eating disorders and substance abuse.
Zimmerman, Amy A
core   +1 more source

Home - About - Disclaimer - Privacy