Results 81 to 90 of about 3,429,470 (304)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The relationship between self-harm and bullying behaviour: results from a population based study of adolescents

open access: yesBMC Public Health, 2021
Background This study aims to better understand the association between bullying behaviour (the bullied, the bullies and the bully-victims) and self-harm, and which protective factors moderate this association. Methods A total of 16,182 adolescents, aged
Ingri Myklestad, Melanie Straiton
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Teenagers whose friends self-harm are more likely to self-harm. [PDF]

open access: yes, 2013
Drug use by friends, low self-esteem, and higher levels of anxiety are all associated with self-harm in teenagers. Having a friend who has self-harmed is one of the most common factors in cases of self-harm among teenagers in Ireland, research has ...

core  

Self-harm following release from incarceration: Patterns and measurement issues

open access: yesInternational Journal of Population Data Science, 2018
Introduction Despite an elevated prevalence of self-harm in the incarcerated adult population, little is known about patterns of self-harm following release from prison.
Rohan Borschmann   +3 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The evaluation of Carousel : a therapeutic programme for prisoners who self-harm [PDF]

open access: yes, 2010
Thesis submitted in partial fulfilment of the requirements of the University of Wolverhampton for the degree of Doctor of Counselling Psychology“Prison self-injury rate accelerates at four times the rise in population” (The Howard League for Penal Reform;
Rose, Julia Margaret Scott
core  

Religion, ethnicity, coping style, and self-reported self-harm in a diverse non-clinical UK population [PDF]

open access: yes, 2011
Previous studies of ethnic and cultural differences in self-harm have focussed on overdose and suicide attempts by South Asian women. Research comparing ethnic groups has rarely examined religion or nationality.
Borrill, J.
core   +1 more source

Prevalence and risk factors for repetition of non-fatal self-harm in Hong Kong, 2002–2016: A population-based cohort study

open access: yesThe Lancet Regional Health. Western Pacific, 2020
Background: A history of self-harm is strongly associated with future self-harm attempts. Large-scale Asian cohort studies examining risk factors for repeated self-harm are lacking. This paper reports on annual prevalence, cumulative risk, annual risk of
Yi Chai, Hao Luo, Paul S.F. Yip
doaj   +1 more source

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