Results 71 to 80 of about 5,603,571 (322)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Mussel Farming Technology Dissemination to the Self Help Groups [PDF]
, 2008 The study is an attempt to assess the socio-economic impact of mussel farming by mobilising the self-help groups in Kerala snd Karnataka coastal belts.
Asokan, P K, Vipinkumar, V P
core
Controlled Clinical Trial of a Self-Help for Anxiety Intervention for Patients Waiting for Psychological Therapy [PDF]
, 2008 This study was a controlled clinical trial in which patients were offered a brief low cost, low intensity self-help intervention while waiting for psychological therapy.
Atha, Chris +6 more
core +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Economic and Social Impacts of Self-Help Groups in India [PDF]
We use a combination of pipeline comparison, propensity score matching, and double differences to evaluate economic and social impacts of a large community driven development program in India.
Deininger, Klaus W., Liu, Yanyan
core +4 more sources
Contingencies of Self-Worth and Social-Networking-Site Behavior [PDF]
, 2011 Social-networking sites like Facebook enable people to share a range of personal information with expansive groups of "friends." With the growing popularity of media sharing online, many questions remain regarding antecedent conditions for this behavior.
Lackaff, Derek +2 more
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Sitting with others: mental health self-help groups in northern Ghana
International Journal of Mental Health Systems, 2012 Background Over the past four decades, there has been increasing interest in Self-Help Groups, by mental health services users and caregivers, alike. Research in high-income countries suggests that participation in SHGs is associated with decreased use ...
Cohen Alex +6 more
doaj +1 more source
Self Help Groups and empowerment of women: Self-selection or actual benefits? [PDF]
Evidence on success of SHGs in empowering females is mixed. In particular, researchers argue that such schemes often attract women who are already active in the public domain (referred to as ‘self-selection’), so that those who are most in need of ...
Dutta, Mousumi +2 more
core +1 more source