Results 81 to 90 of about 245,700 (287)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

A Very Low Complexity Successive Symbol-by-Symbol Sequence Estimator for Faster-Than-Nyquist Signaling

open access: yesIEEE Access, 2017
In this paper, we investigate the sequence estimation problem of binary and quadrature phase shift keying faster-than-Nyquist (FTN) signaling and propose two novel low-complexity sequence estimation techniques based on concepts of successive interference
Ebrahim Bedeer   +2 more
doaj   +1 more source

Sliding Window Spectrum Sensing for Full-Duplex Cognitive Radios with Low Access-Latency

open access: yes, 2016
In a cognitive radio system the failure of secondary user (SU) transceivers to promptly vacate the channel can introduce significant access-latency for primary or high-priority users (PU).
Afisiadis, Orion   +3 more
core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Optimized Full-Duplex MIMO DF Relaying With Limited Dynamic Range

open access: yesIEEE Access, 2017
This paper investigates the transceiver optimization of full-duplex multiple-input multipleoutput decode-and-forward (DF) relaying by taking into account the practical factor of limited dynamic range (LDR).
Hong Shen   +3 more
doaj   +1 more source

Full-Duplex Operations in Wireless Powered Communication Networks

open access: yes, 2017
In this paper, a wireless powered communication network (WPCN) consisting of a hybrid access point (H-AP) and multiple user equipment (UEs), all of which operate in full-duplex (FD), is described.
Ju, Hyungsik, Kim, Tae-Joong, Lee, Yuro
core   +2 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Full-Duplex Femto Base-Station With Antenna Selection: Experimental Validation

open access: yesIEEE Access, 2019
Full-Duplex (FD) is an emerging technology that allows the communication device to use the same frequency to simultaneously transmit and receive. The cancellation of the high power Self-Interference (SI) is the main challenge in FD systems.
Nidal Zarifeh   +3 more
doaj   +1 more source

Cancellation of Power Amplifier Induced Nonlinear Self-Interference in Full-Duplex Transceivers

open access: yes, 2014
Recently, full-duplex (FD) communications with simultaneous transmission and reception on the same channel has been proposed. The FD receiver, however, suffers from inevitable self-interference (SI) from the much more powerful transmit signal.
Anttila, Lauri   +3 more
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

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