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Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Dialectic, Drama and Self-Knowledge in Plato’s Charmides [PDF]
[Language of the article: Greek] Charmides is a dialogue highly indicative of the importance that the prologues to Plato’s works have for our understanding of the whole spirit and philosophical content of each dialogue as a whole. It is representative of
Melina G. Mouzala
doaj
Extremism: A cover for ignorance
The explanation of the relation between religiousness (being religious; doing according to one’s religion’s recommendations) and extremism depends on the different types of religiousness.
Zeinab Barkhordari
doaj +1 more source
Exemplars, Institutions, and Self-Knowledge in Schopenhauer as Educator [PDF]
As a face in the mirror, so the morals of men are easily corrected with an exemplar.As Christopher Janaway observed, “the topic of Schopenhauer as Educator is really education rather than Schopenhauer.”2 Indeed, Nietzsche described it as addressing a ...
Golob, Sacha
core
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Intimate Selves: A Poetic Inquiry into Self-Knowledge [PDF]
This article uses poetic inquiry to explore the author’s experiences of the global COVID-19 pandemic, which brought about a State of Disaster in South Africa from 26 March 2020 to 5 April 2022.
Deirdre Byrne
doaj +1 more source
Authority without privilege: How to be a Dretskean conciliatory skeptic on self-knowledge [PDF]
Dretske is a “conciliatory skeptic” on self-knowledge. Take some subject S such that S thinks that P and S knows that she has thoughts. Dretske’s theory can be put as follows: S has a privileged way of knowing what she thinks, but she has no privileged ...
Roche, Michael, Roche, William
core
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
The aging self: how older men and women reflect on themselves and others
ObjectivesSelf-relevant stimuli, such as one’s name or face, are prioritised by the brain, leading to faster responses and enhanced attentional processes.
Marta Paź, Anna Nowicka
doaj +1 more source
Analytical Examination of the Philosophical Correlations between "Self-Knowledge" and "Knowledge of the Lord" with a Focus on the Relationship between Soul and Body [PDF]
One of the most important traditions regarding the connection between self-knowledge and the knowledge of God is the tradition "He who knows himself knows his Lord." This narration has been examined, explained, and analyzed by many Muslim thinkers. Among
Mohammad Javad Jafari Zadeh +2 more
doaj +1 more source

