Results 101 to 110 of about 6,218,857 (350)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Self-Medication Behavior: Self-Medication Behavior

Journal of Midwifery and Nursing, 2020
In developing countries self-medication behavior is something that is very often found. This happens because self-medication behavior provides a cheaper and easier alternative for the community. Coupled with the ease in purchasing drugs. Self-medication is usually done to overcome complaints and minor illnesses that are often experienced by the ...
openaire   +1 more source

Self-medication amongst university students of Karachi: prevalence, knowledge and attitudes [PDF]

, 2008
OBJECTIVE: To determine the prevalence, attitude and knowledge of self-medication amongst university students of Karachi, Pakistan. METHODS: This cross-sectional, study was conducted from Jan-Feb 2007.
Saleem, Sarah, Shahid, Saman, Shaikh, Mehrine, Syed, Reema, Vaqar, Talha, Waqar, Sana, Yousaf, Wajeeha, Zafar, Syed Nabeel, Zubairi, Akbar Jaleel   +8 more
core   +1 more source

Knowledge, practices and attitudes on antibiotics use in Cameroon: Self-medication and prescription survey among children, adolescents and adults in private pharmacies

PLoS ONE, 2019
Benefits of antibiotics are threatened by the self-medication, people’s lack of knowledge and inappropriate use of antibiotics, especially in developing countries. This study was designed to determine knowledge; attitudes and practices toward antibiotics
Grace-Ange Elong Ekambi, C. Okalla Ebongue, I. Penda, Emmanuel Nnanga Nga, Emmanuel Mpondo Mpondo, C. E. Eboumbou Moukoko   +5 more
semanticscholar   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Development and psychometric properties of a self-medication behavior inventory

Frontiers in Psychology
IntroductionSelf-medication is a prevalent behavior with significant health implications. Understanding its psychosocial determinants can inform preventative strategies and interventions.MethodsWe evaluated the psychometric properties of the Self ...
Julio C. Penagos-Corzo, Melissa J. Ortiz-Barrero, Reneé Hernández-Ramírez, Yavne Ochoa-Ramírez, Regina González Ehlinger, Andrés M. Pérez-Acosta   +5 more
doaj   +1 more source

Evaluation of a new trauma-related drinking to cope measure: Latent structure and heritability [PDF]

, 2019
Posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) commonly co-occur, share latent genetic risk, and are associated with many negative public health outcomes.
Aggen, Steven H., Amstadter, Ananda B, PhD, Dick, Danielle, Hawn, Sage E.   +3 more
core   +1 more source

Dispensing of antimicrobials in Kenya : a cross sectional pilot study and its implications [PDF]

, 2018
Objectives: Irrational use of antibiotics is a major driver of antimicrobial resistance, enhanced by inappropriate prescribing and dispensing of antibiotics.
Godman, Brian, Mukokinya, Mwasi Mary Ann, Oluka, Margaret, Opanga, Sylvia   +3 more
core   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Prevalence of Self-Medication among the Elderly in Gorgan, North of Iran

Journal of Clinical and Basic Research, 2018
Background and objectives: Self-medication is a major global health problem. Regarding this issue, the elderly are one of the most vulnerable groups in the community.
Yaghoub Shayeste, Danial Jafari, Reza Hosseinpour, Shaghayegh Daie   +3 more
doaj