Results 91 to 100 of about 5,584,238 (297)
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
PLoS ONE, 2009 Self-medication is a specific therapeutic behavioral change in response to disease or parasitism. The empirical literature on self-medication has so far focused entirely on identifying cases of self-medication in which particular behaviors are linked to ...
Michael S Singer +2 more
doaj +1 more source
Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up
Molecular Oncology, EarlyView.This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source
A pilot program at the worksite to reduce adverse self-medication behaviors
, 2009 Patricia J Neafsey1,2, Gregory Lutkus2, Jessica Newcomb2, Elizabeth Anderson1,21Center for Health Intervention and Prevention (CHIP); 2School of Nursing, University of Connecticut, Storrs, CT, USAAbstract: A Next Generation Personal Education Program ...
Gregory Lutkus +3 more
core
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Self-efficacy for medication management: a systematic review of instruments
, 2018 Larkin Lamarche, Ambika Tejpal, Dee Mangin Department of Family Medicine, McMaster University, Hamilton, ON, Canada Background: Medication self-efficacy is a potentially important construct in research around optimal use of prescription medications.
Tejpal A, Lamarche L, Mangin D
core
, 2016 Self-reported reasons for medication non-adherence among epileptic patients at Yirgalem General Hospital.
Temesgen Yohannes Hasiso (3184713) +1 more
core +1 more source
Communication Predicts Medication Self-Efficacy in Glaucoma Patients [PDF]
, 2016 Medication self-efficacy, or patients’ confidence that they can perform medication-related behaviors, is associated with better glaucoma medication adherence. Little is known about how to enhance glaucoma patients’ medication self-efficacy.
Carpenter, Delesha M. +17 more
core +1 more source