Results 81 to 90 of about 5,584,238 (297)

Self-medicating scale. Outcomes measurement tool: drug use behaviour – self-medication .

, 2008
This scale measures people’s beliefs about self-medication. It measures reluctance to self-mediate, ease of self-medication and beliefs about letting things run their ...
French, David P, James, Delyth H
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Characteristics of self-medication practice among self-medicated people.

, 2022
(A) representing how often respondents self-medicated; (B) representing the different sources of self-medication where X-axis indicates the percentage of population and Y-axis indicates sources of medication; (C) representing the most common self ...
H. M. Hamidullah Mehedi (12082844), Mohammad Imdad Hussain (12867337), Nusrat Afrin (12867328), Sabuj Kanti Mistry (7305518), Ashim Barua (12867340), Afrah Rashid (12867316), Prashanta Chakraborty (12867331), Md. Emran (12867334), Nowshin Tarannum (12867319), Tonmoy Chowdhury (12867325), Srabanty Das (12867322), Kay Kay Shain Marma (11725544), Ayan Saha (12867313)   +12 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Self-medication patterns among Libyan University Medical students

Self-medication, the practice of using medications without professional guidance, is a significant public health concern globally, particularly among medical students who, despite their pharmacological training, often engage in this practice at high ...
Ahmed E. Atia
core   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Are attitudes towards medication adherence associated with medication adherence behaviours among patients with psychosis? A systematic review and meta analysis [PDF]

, 2013
Background Studies have shown patient attitudes to be an important predictor for health related behaviours including medication adherence. It is less clear whether patient attitudes are also associated with medication adherence among patients with ...
McCabe, R., McCabe, R, Richardson, M, Priebe, S, Priebe, S., Richardson, M.   +5 more
core   +1 more source

Self-medication among medical students in Anbar and Fallujah Universities – Iraq

مجلة كلية الطب, 2018
Background: Self-medication (SM) is a worldwide issue, that has serious adverse effects on individuals and communities. Objective:  To estimate the prevalence of self- medication   among medical student in Anbar and Falluja Universities and to explore
Ameel F. Al Shawi, Ahmed F. Ali, Murtadha M. Enad,  Junaid A. Salih   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source