Results 111 to 120 of about 5,719,277 (332)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Kajian Perilaku Swamedikasi Menggunakan Obat Penggemuk Badan oleh Pasien Pengunjung Apotek di Kota Kupang Tahun 2016 [PDF]

, 2017
Community efforts to treat themselves are known as self-medication. Self-medication is usually done to treat complaints and minor ailments. The Sudan Journal of Rational Use of Medicine (2014) found 7 categories of drugs most widely used in self ...
Lenggu, M. Y. (Maria)
core   +1 more source

Prevalence and determinants of the use of self-tests by members of the public: a mixed methods study [PDF]

, 2006
Background Self-tests can be used by members of the public to diagnose conditions without involving a doctor, nurse or other health professional. As technologies to design and manufacture diagnostic tests have developed, a range of self-tests have ...
A Figueiras, A Scott, Angela Ryan, British Medical Association Board of Science, C Bradley, C Pope, CA Ford, E O'Brien, F Payne, FA Stevenson, Human Genetics Commission, J Erwin, J Kitzinger, J Ritchie, JM Morse, LJ Haddow, MC Weiss, MH Merson, MQ Patton, Office of Population Censuses and Surveys, Parliamentary Office of Science and Technology, R Krueger, S Coster, S Wilson, Sheila Greenfield, Sue Wilson, YouGov Limited   +26 more
core   +4 more sources

Self-Medication Among King Khalid University Students, Saudi Arabia

Risk Management and Healthcare Policy, 2019
Purpose This study objective was to explore the pattern of self-medications among King Khalid University students, Saudi Arabia. Patients and methods A cross-sectional study was conducted over five months among King Khalid University students, Abha ...
Sultan M. Alshahrani, S. Alavudeen, K. Alakhali, Y. Al-Worafi, Ahmed K Bahamdan, E. Vigneshwaran   +5 more
semanticscholar   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Self-medication among medical students in Anbar and Fallujah Universities – Iraq

مجلة كلية الطب, 2018
Background: Self-medication (SM) is a worldwide issue, that has serious adverse effects on individuals and communities. Objective:  To estimate the prevalence of self- medication   among medical student in Anbar and Falluja Universities and to explore
Ameel F. Al Shawi, Ahmed F. Ali, Murtadha M. Enad,  Junaid A. Salih   +3 more
doaj   +1 more source

Mediating Effect of Self-Efficacy on the Relationship Between Medication Literacy and Medication Adherence Among Patients With Hypertension

Frontiers in Pharmacology, 2020
Background: Studies have reported that medication literacy had a positive effect on medication adherence in patients with hypertension. However, little is known about the mechanism underlying this relationship in patients with hypertension.Objective: The
Zhiying Shen, Zhiying Shen, Zhiying Shen, Shuangjiao Shi, Shuangjiao Shi, Siqing Ding, Siqing Ding, Zhuqing Zhong, Zhuqing Zhong   +8 more
doaj   +1 more source

Self-Medication in Animals

Science, 2013
Animal self-medication against parasites is more widespread than previously thought, with profound implications for host-parasite biology.
de Roode, J. C., /Lefèvre, Thierry, Hunter, M. D.   +2 more
openaire   +2 more sources

Self‐medication with alcohol or drugs for mood and anxiety disorders: A narrative review of the epidemiological literature

Depression and Anxiety, 2018
The comorbidity of mood and anxiety disorders (MD and AD) with substance use disorders (SUD) is common. One explanation for this comorbidity is the self‐medication hypothesis, which posits that individuals with MD or AD use substances to cope with the ...
S. Turner, Natalie P Mota, J. Bolton, J. Sareen   +3 more
semanticscholar   +1 more source