Results 41 to 50 of about 490,195 (259)

The Use of Operational-Technical Measures Against Participants in the Anti-Soviet Resistance

open access: yesGenocidas ir Rezistencija
The KGB used various covert measures aimed primarily at gathering intelligence information. While agents were the KGB’s main tools, in some cases covert technical measures proved more effective in collecting information.
Kristina Burinskaitė
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Nuancen in Grün: Betrieb eines institutionellen und disziplinären Repositoriums – Erfahrungen und Entwicklungen an der Saarländischen Universitäts- und Landesbibliothek / Shades of green: Maintaining both an institutional and a disciplinary repository – experiences and current developments at Saarland University and State Library

open access: yesGMS Medizin – Bibliothek – Information, 2009
Since the year 1999 Saarland University and State Library (Germany) is offering EPublishing services in the form of an Open Access repository. Due to its triple role as a University Library, a State Library and as the Special Subject Library for ...
Müller, Matthias, Herb, Ulrich
doaj  

Self-published book design: statement of the problem

open access: yesАрхитектон
The article problematizes the study of self-published book design — a field of inquiry at the intersection of design, book culture, and key vectors of sociocultural development that remains largely overlooked by scholars.
Gramatchikov Yaroslav D.
doaj   +1 more source

Publishing to Progress Science: Shifting the Paradigm from Self to Selfless

open access: yesMarshall Journal of Medicine, 2016
“Publish or perish" is a phrase coined to describe the pressure in academia to rapidly and continually publish academic work to sustain or further one's career to the next level of academic promotion and to build an academic reputation1.
Darshana T. Shah
doaj   +1 more source

Sharing your work by self-archiving: encouragement from the Journal of the Medical Library Association

open access: yesJournal of the Medical Library Association, 2020
Self-archiving offers opportunities for authors to more broadly disseminate their work—both in pre-print form before its submission to a journal and in post-print form after its acceptance and publication in a journal.
Abigail Goben, Katherine G. Akers
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Creative Users, Social Networking, and New Models of Publishing

open access: yesCultural Science, 2014
This paper reviews the changing landscape of the publishing industry, which is being reshaped by dynamics of user co-creation, social networking and open licencing.
Ren Xiang
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

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