Results 81 to 90 of about 397,121 (285)

You don’t know what you’ve got till it’s gone: the changing landscape of UK learned society publishing

open access: yesInsights: The UKSG Journal
This study draws on a longitudinal dataset of 277 UK learned societies covering the period 2015–2023 to provide evidence-based insights into the changing landscape of society publishing.
Rob Johnson, Elle Malcolmson
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Blessed. Un fanzine sobre publicidad y religión [PDF]

open access: yes, 2018
La comunicación visual tiene un valor inmensurable en la actualidad ya sea a través del diseño, la ilustración, la fotografía o la propia publicidad. Este Trabajo Fin de Grado consiste en la investigación sobre la posibilidad de creación de un proyecto ...
Navarro Carvajal, Anouk
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Textbooks in transitional countries: Towards a methodology for comparative analysis

open access: yesKnjižnica, 2004
In its first part, the paper analyses the ambiguous nature of the book as a medium: its physical production and its distribution to the end user takes place on a market basis; on the other hand, its content is predominantly consumed in a sector that was ...
Miha Kovač, Mojca Kovač Šebart
doaj   +1 more source

The Apple E-Book Agreement and Ruinous Competition: Are E-Goods Different for Antitrust Purposes? [PDF]

open access: yes, 2014
Publishers have spent the last decade and a half struggling against falling prices for digital goods. The recent antitrust case against Apple and the major publishers highlights collusive price fixing as a potential method for resisting depreciation ...
Wolfe, Michael
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Marketing Your Knowledge: A Report to Philanthropy's R&D Organizations [PDF]

open access: yes, 2003
Examines obstacles to the sharing of knowledge among philanthropic organizations.

core  

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

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