Results 81 to 90 of about 1,072,525 (265)
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Animals, 2016 While the role of the horse in riding hazards is well recognised, little attention has been paid to the role of specific theoretical psychological processes of humans in contributing to and mitigating risk.
Jodi DeAraugo +3 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Inclosures, Vagueness, and Self-Reference
Notre Dame Journal of Formal Logic, 2010 In this paper, I start by showing that sorites paradoxes are inclosure paradoxes. That is, they fit the Inclosure Scheme which characterizes the paradoxes of self-reference. Given that sorites and self-referential paradoxes are of the same kind, they should have the same kind of solution. The rest of the paper investigates what a dialetheic solution to
openaire +3 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Relendo a perspectividade: algumas notas sobre "o perspectivismo de Nietzsche"
Cadernos NietzscheEste texto contrasta o entendimento comum do "perspectivismo de Nietzsche" com o seu uso da palavra "Perspektive" e termos semelhantes. As primeiras seções proporcionam uma breve pesquisa do desenvolvimento dos diversos significados através da carreira ...
Jakob Dellinger
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Parametrized Quotation and Self-Reference
Electronic Notes in Theoretical Computer Science, 2003 AbstractThis paper is concerned with the theoretical issues surrounding the specification of self-applicative computer programs. In particular we seek to explain the competing requirements desireable of any formal system that admits both of self-r eference and quotation, and present three new solutions to the not inconsiderable problems encountered ...
openaire +1 more source