Results 61 to 70 of about 1,050,940 (286)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Participation in sport and exercise requires self-regulation. Examples of self-regulation include an individual fighting the urge to stop during an intense exercise class; a golfer trying to ignore feelings of excitement and focus on a simple putt to win a tournament; and a soccer player resisting the desire to strike an opponent who has repeatedly ...
JONES, Marc, TURNER, Martin
openaire +2 more sources
Push and Pull Between the Public and Professional
In order to protect research subjects and to improve patient care, ongoing examination about whether medicine should be a self-regulating profession, or whether the general public should have a role in setting guidelines for the ethical conduct of ...
Lillian Ringel
doaj +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
A repeated game of self regulation
Este artículo investiga teóricamente los incentivos presentes en la autorregulación desde una perspectiva agente-principal y en un contexto de interacción repetida entre una Organización Autorregulada (OA) y consumidores que no pueden observar ...
Javier Núñez Errazuriz
doaj
HUBUNGAN REGULASI DIRI DENGAN FEAR OF MISSING OUT PADA PENGGUNA TIKTOK DEWASA AWAL [PDF]
Social media has become an important part of the daily lives of many individuals, especially among early adulthood. One of the popular social media platforms is TikTok. Majority TikTok users in Indonesia come from early adulthood, in age range from 18 to
Febriani, Mutia Indria
core
Sustainable bioplastics manufacturing from renewable sources
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto +6 more
wiley +1 more source
Self-regulation of the reconnecting current layer in relativistic pair plasma reconnection [PDF]
We investigate properties of the reconnecting current layer in relativistic pair plasma reconnection. We found that the current layer self-regulates its thickness when the current layer runs out current carriers, and so relativistic reconnection retains ...
Hesse, M., Zenitani, S.
core +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source

