Results 71 to 80 of about 5,139,684 (305)

Procrastination: The Role of Self Regulation And Anxiety

Psikoislamika, 2023
Tujuan diadakan penelitian ini adalah untuk mengkaji Self Regulation dan kecemasan sebagai prediktor prokrastinasi pada mahasiswa. Penelitian merupakan jenis penelitian kuantitatif korelasional. Sampel yang digunakan sejumlah 100 subjek. Data dikumpulkan
Tsafitri Rinti Taddaga, Siti Khorriyatul Khotimah   +1 more
doaj  

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Training strategies for self-regulating motivation and volition: effect on Learning

Anales de Psicologia, 2017
The objective of this work is to determine the relative and combined effect on self-regulation and learning of teaching students two kinds of self-regulation strategies, the first centered on motivation, and the second on negative emotions that obstruct ...
Mario Baez-Estradas, Jesús Alonso-Tapia
doaj   +1 more source

Self-Control and Affect Regulation Styles Predict Anxiety Longitudinally in University Students

Collabra: Psychology, 2020
The performance and well-being of university students is influenced by many factors, including self-control and affect regulation, but little is known about how these factors relate.
John P. Powers, Hannah Moshontz, Rick H. Hoyle   +2 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Self-regulation in securities markets

, 2011
This paper canvasses the trends in self-regulation and the role of self-regulation in securities markets in different parts of the world. The paper also describes the conditions in which self-regulation
John Carson, Carson, John
core   +1 more source

Self-compassion in somatoform disorder [PDF]

, 2018
‘Third wave’ cognitive-behavioral therapies have given a boost to the study of resilience factors, such as self-compassion. To get an indication of the potential clinical relevance of self-compassion for somatoform disorder, this study examined whether ...
Scholten, R., van Broeckhuysen-Kloth, S., Rinie Geenen, Dewsaran-van der Ven, C., Ron Scholten, Thorsell, S., Leerstoel Geenen, Stress and self-regulation, Shiva Thorsell, Saskia van Broeckhuysen-Kloth, Van Broekhuysen-Kloth, S., Charlotte Dewsaran-van der Ven, Véronique De Gucht, De Gucht, V., Geenen, R.   +14 more
core   +1 more source

Development of a guidance to improve allied primary healthcare after acquired brain injury in the Netherlands – a mixed-methods study

BMC Primary Care
Background The organisation of primary care for individuals with acquired brain injury (ABI) and collaboration in primary care rehabilitation requires improvement.
Gerbrich Douma, Paulien H. Goossens, Ton Satink, Kitty Jurrius, Maud Graff, Lucas Koester, Hubertus J. M. Vrijhoef   +6 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source