Results 91 to 100 of about 7,266,760 (300)

Advancing Cervical Cancer Prevention Equity: Innovations in Self-Sampling and Digital Health Technologies Across Healthcare Settings

Diagnostics
Cervical cancer causes 350,000 deaths annually, with 90% occurring in low- and middle-income countries (LMICs), despite being largely preventable through vaccination and screening.
Michelle Gomes, Elena Provaggi, Andrea Barnabas Pembe, Adeola Olaitan, Aleksandra Gentry-Maharaj   +4 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Assessment of HPV screening modalities within primary care: a systematic review

Frontiers in Medicine
IntroductionMost cervical cancer precancerous lesions are associated with high-risk human papillomavirus (HPV) subtypes. Early detection through screening is crucial for preventing and managing HPV-related diseases.
Yahya Mostafa Waly, Abu-Baker Sharafeldin, Abdulrahman Al-Majmuei, Mohammad Alatoom, Salim Fredericks, Adri-Anna Aloia   +5 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Direct-to-Consumer Testing: A Game-Changer for STI Control and Public Health? A Critical Review of Advances Since the Onset of the COVID-19 Pandemic

Venereology
The COVID-19 pandemic disrupted routine healthcare services, including testing and treatment for sexually transmitted infections (STIs). At the same time, it fostered optimism about the potential of direct-to-consumer (DTC) self-testing solutions, fueled
David F. Martín-García, Julien Santi-Rocca   +1 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Self-beliefs and bullying : unravelling the relation between bullying, being bullied and self-concept for upper elementary school aged children

, 2006
Previous examinations of relations between bullying, victimisation, and self-concept have been flawed by erroneous research practices such as the un-attenuated use of dichotomous variables to measure relationships between continuous variables (Finger ...
Finger, Linda R., Dowson, Martin, Craven, Rhonda   +2 more
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Syndemic Synergy of HPV, HIV, and HSV-2 for Oncogenic HPV Replication in Female Sex Workers

Tropical Medicine and Infectious Disease
Background: Female sex workers (FSWs) in sub-Saharan Africa bear a disproportionate burden of sexually transmitted infections, including HIV, high-risk HPV (HR-HPV), and herpes simplex virus type 2 (HSV-2).
Jonathan Muwonga Tukisadila, Ralph-Sydney Mboumba Bouassa, Serge Tonen-Wolyec, Hugues Loemba, Jeremie Muwonga, Laurent Belec   +5 more
doaj   +1 more source

Use of OC curves in quality control with an example of sampling for mycotoxins [PDF]

, 2011
An ‘operating characteristics’ (OC) curve is a simple tool that has been in use in quality control for many years but does not seem to be widely applied in the particulate sampling field.
Bourgeois, Florent, Littlemier, Sheryl, Lyman, Geoffrey   +2 more
core