Results 101 to 110 of about 7,266,760 (300)

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Self-sampling HPV test in women not undergoing Pap smear for more than 5 years and factors associated with under-screening in Taiwan

open access: yesJournal of the Formosan Medical Association, 2016
Under-utilization of Papanicolaou (Pap) smear causes a gap in the prevention of cervical neoplasms. A prospective population-based study was conducted investigating whether a self-sampling human papillomavirus (HPV) test was feasible for under-users of ...
Hung-Hsueh Chou   +18 more
doaj   +1 more source

The relation of self-concept to desirable educational outcomes

open access: yes, 2006
Reviewers (Byrne, 1996a, 1996b; Hattie, 1992; Marsh, Byrne, & Shavelson, 1988; Marsh & Craven, 1997; Craven, Marsh, & Burnett, 2003) consider that self-concept is multifaceted and espouse that self-concept cannot be adequately understood if its ...
Craven, Rhonda   +3 more
core  

A jackknife variance estimator for self-weighted two-stage samples

open access: yes, 2013
Self-weighted two-stage sampling designs are popular in practice as they simplify field-work. It is common in practice to compute variance estimates only from the first sampling stage, neglecting the second stage.
Escobar, E.L., Berger, Y.G.
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Letter to the editor

open access: yesClinical Epidemiology, 2016
Annika Linde, Amelie Plymoth Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden It was with great interest that we noticed that other researchers are also interested in participant-collected nasal ...
Linde A, Plymoth A
doaj  

A comprehensive multilevel model meta-analysis of self-concept interventions

open access: yes, 2006
The efficacy of self-concept interventions has previously been examined through traditional meta-analytic methods, and a host of moderators of intervention outcomes have been identified (O’Mara, Marsh, & Craven, 2004; Haney & Durlak, 1998; Hattie, 1992).
Craven, Rhonda   +2 more
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Body image and self-concept in adolescent girls

open access: yes, 2006
Anorexia Nervosa has been recently recognized as one of the most common chronic illnesses that affects the female adolescent population today. Although there has been an abundance of research into eating disorders in a variety of fields, significant ...
Halse, Christine   +3 more
core  

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