Results 51 to 60 of about 4,508,597 (303)
Moving forwardbuilding self-sufficiency grant proposal [PDF]
, 2007 Includes bibliographical ...
Humphrey, Rebecca
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The self‐sufficient services fallacy [PDF]
Frontiers in Ecology and the Environment, 2009 Published ...
openaire +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Regional non-equilibrium characteristics and spatial convergence of China’s self-sufficiency rate of rations [PDF]
Ziyuan Kexue[Objective] This article discussed the regional differences and spatial convergence of ration security from the perspectives of consumption and demand, in order to provide a scientific basis for each region to better assume the due responsibility of ...
YANG Yidan, YAO Chengsheng, GAO Yunpeng, LIU Weifang
doaj +1 more source
Self-sufficient sets in smartgrids
Electronic Notes in Discrete Mathematics, 2018 Abstract We consider the problem of finding microgrids in a network. We mainly focus on the complexity aspects related to the different variants of this problem5.
J. David +3 more
openaire +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Long-Term Agricultural Development Problems of the Russian Far East [PDF]
Пространственная экономика, 2012 The article considers the problems of long-term agricultural development and prospects of scientifictechnical and technological modernization. The author justifies two versions of the perspective agricultural development and opportunities for the local ...
Grigory Isakovich Sukhomirov +1 more
doaj +1 more source