Results 51 to 60 of about 35,880 (264)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

La question de l’autosuffisance protéique est-elle définitivement obsolète pour l’Union Européenne ?

Oléagineux, Corps gras, Lipides, 2005
Is the issue of European self-sufficiency in vegetal proteins definitely obsolete? The issue is reviewed from two standpoints: economic relevance and political feasibility in regards to international relations.
Mahé Louis-Pascal
doaj   +1 more source

Urban-rural relations in renewable electric energy supply – the case of a German energy region

International Journal of Sustainable Energy Planning and Management, 2019
The study analyzes the cross-linking of urban and rural regions in terms of synergies between electric energy supply from renewables and electric energy demand by taking the example of a  German energy region.
Caroline Möller, Martin Faulstich, Sandra Rosenberger   +2 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Rooftop Photovoltaic for Residential Electricity Self-Sufficiency: Assessing Potential Benefits in Major Japanese Cities

Urban Science
Rooftop photovoltaic (RTPV) systems have the potential to significantly boost residential electricity self-sufficiency in urban areas. However, estimating the self-sufficiency potential of each city is challenging due to the trade-off between target ...
Samuel Matthew G. Dumlao, Chuyue Yan, Seiichi Ogata   +2 more
doaj   +1 more source

Comparative Advantage, Self-sufficiency and Food Security in Iran: Case Study of Wheat Commodity [PDF]

International Journal of Agricultural Management and Development, 2014
Food security has a dynamic notion during the time and may be affected by various domestic and global factors. Nevertheless, Iranian policy makers consider food security as same as self-sufficiency in agricultural food products, particularly wheat ...
Mahmood Haji-Rahimi
doaj