Self-Knowledge and Self-Love [PDF]
In this paper I argue for the claim that self-love is a precondition for self-knowledge. This claim is relevant to the contemporary philosophical debate on self-knowledge, but mainly because it draws attention to the role of claims of self-knowledge in the larger context of our ordinary practice of rationalizing and appropriating our actions.
openaire +2 more sources
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Bioinspired Compartmentalization Strategy for Coating Polymers with Self-Organized Prismatic Films
Zhengzheng Li +13 more
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Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Analysis of Synaptic Scaling in Combination with Hebbian Plasticity in Several Simple Networks
Conventional synaptic plasticity in combination with synaptic scaling is a biologically plausible plasticity rule that guides the development of synapses towards stability.
Christian eTetzlaff +4 more
doaj +1 more source
ASSESSMENT OF IMPULSIVITY AND THE DEVELOPMENT OF SELF‐CONTROL IN STUDENTS WITH ATTENTION DEFICIT HYPERACTIVITY DISORDER [PDF]
Nancy A. Neef +2 more
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AGRICULTURAL DEVELOPMENT, STATE EFFECTIVENESS AND LONG-RUN ECONOMIC DEVELOPMENT [PDF]
This paper begins with the presumption that rapid economic development requires an effective state. An effective state is able to act independently of powerful interest groups with the aim of allocating resources so as to maximize long-term economic ...
Richard Grabowski, Sharmistha Self
core
Williams’s Pragmatic Genealogy and Self-Effacing Functionality [PDF]
In Truth and Truthfulness, Bernard Williams sought to defend the value of truth by giving a vindicatory genealogy revealing its instrumental value. But what separates Williams’s instrumental vindication from the indirect utilitarianism of which he was a ...
Queloz, Matthieu
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Individual Self, Relational Self, Collective Self: Hierarchical Ordering of the Tripartite Self
The individual self comprise unique attributes, the relational self comprises partner-shared attributes, and the collective self comprises ingroup-shared attributes. All selves are fundamental components of the self-concept, with each being important and meaningful to human experience and with each being associated with health benefits. Are the selves,
Sedikides, Constantine +2 more
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