Results 111 to 120 of about 12,973,361 (304)

Self-Directed Learning for the 21st Century

, 2019
This book is devoted to scholarship in the field of self-directed learning in the 21st century, with specific reference to higher education. The target audience of the book includes scholars in the field of self-directed learning and higher education ...
du Toit, Adri, Johnson, David W., Lubbe, Anitia, Golightly, Aubrey, Johnson, Roger T., Olivier, Jako, van Zyl, Sukie, Bergamin, Per B., Kruger, Corné, van der Westhuizen, Christo, Goede, Roelien, Laubscher, Dorothy, Bosch, Chantelle   +12 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Who's on first? : causal ordering of ademic self-concept, motivational goals, and achievement

, 2004
Investigating causal relations between self-concept and motivational goals represents a leading edge in self-concept research. The objective of the study was to determine the nature and extent of causal relations between students’ academic self-concept ...
Dowson, Martin, Barker, Katrina L., McInerney, Dennis M.   +2 more
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Untangling the web : reports of self-concept, academic motivation and perceived discrimination for indigenous secondary students

, 2006
Recently, a new direction has emerged within the field of educational psychology that has sought to address the inequities between Indigenous Australian students and the wider Australian student population.
Craven, Rhonda, Bodkin-Andrews, Gawaian
core  

Motility-induced mixing transition in exponentially growing multicellular spheroids

Communications Physics
Growth drives cellular dynamics in dense aggregates, including bacterial colonies, developing tissues, and tumors. However, its effects on other relevant activities have not received sufficient attention.
Torben Sunkel, Lukas Hupe, Philip Bittihn   +2 more
doaj   +1 more source

Robustness of ballistic transport in antidot superlattices

New Journal of Physics, 2019
The magneto-resistance of antidot lattices shows pronounced peaks, which became a hallmark of ballistic electron transport. While most studies agree that they reflect the interplay of regular and chaotic motion in the quasi-classical dynamics, the exact ...
George Datseris, Theo Geisel, Ragnar Fleischmann   +2 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

PolicySegNet: a policy-based reinforcement learning framework with pretrained embeddings and transformer decoder for joint brain tumors segmentation and classification in MRI

The Egyptian Journal of Radiology and Nuclear Medicine
PolicySegNet is a novel hybrid deep learning architecture developed for joint brain tumor segmentation and classification using MRI scans. It combines a pretrained SegFormer-B4 encoder (with a MiT backbone, originally trained on the ADE20K dataset) as a ...
Vishv Patel, Vandana Patel, Aakash Shinde   +2 more
doaj   +1 more source