Results 61 to 70 of about 14,359,458 (301)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Frontiers in Digital HealthBackgroundSemantic interoperability remains a significant barrier in healthcare, particularly when integrating patient-reported, clinical, and genomic data to enable personalized care.
Radha Ambalavanan +5 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Contact numbers in packings of frictional cylinders [PDF]
EPJ Web of ConferencesThe mechanical stability of a granular system depends on the average number of contacts Z between its particles. For most particle shapes, predicting Z as a function of the average volume fraction ϕ is complicated by the spatial correlations between ...
Schröter Matthias +2 more
doaj +1 more source
Applied Bionics and Biomechanics, 2022 The aim of this study is to demonstrate the effect of particle size on semiconductor properties; artificial intelligence is being used for the research methods.
Walid Theib Mohammad +11 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Controlling molecular transport in minimal emulsions
Nature Communications, 2016 Emulsion droplets have many biotechnological applications, such as parallelized single cell analysis. Here, Gruner et al. introduce the concept of the minimal emulsions in a microfluidic device that allows full control of molecular transport between ...
Philipp Gruner +6 more
doaj +1 more source
Minimum entropy production by microswimmers with internal dissipation
Nature Communications, 2023 The energy dissipation and entropy production by self-propelled microswimmers differ profoundly from passive particles pulled by external forces.
Abdallah Daddi-Moussa-Ider +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Assessing undergraduate and postgraduate hard and soft skills in analytics and data science courses [PDF]
, 2016 Traditional approaches to assessing undergraduate assignments in the field of software related courses, including Analytics and Data Science courses, involve the course tutors in reading the students’ code and getting the students to physically ...
Self, Richard
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