LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
An investigation of volcanic gases and dust (aerosols) in the stratosphere [PDF]
There are no author-identified significant results in this ...
Decker, R. W., Self, S.
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Review of Ann Murray, ed. Germanistik in Ireland, Interrogating Normalcy
Forum, 2014 Germanistik in Ireland, Interrogating Normalcy, edited by Ann Murray, is a rich and diverse collection of essays from postgraduate students within German Studies.
Lizzy Robinson-Self
doaj +3 more sources
Sediment transport and erosion in the Fourchon area of Lafourche parish [PDF]
NASA aerial photography in the form of color infrared and color positive transparencies is used as an aid in evaluating the rate and effect of erosion and sediment transport in Bay Champagne ...
Self, R. P., Whitehurst, C. A.
core +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Effect of Lateral Body Position on Heart Rate Variability in Patients with Sleep Apnea Syndrome
Journal of Arrhythmia, 2007 Sleep apnea syndrome (SAS) can exacerbate cardiovascular disease by augmenting activity of the sympathetic nervous system. One method of treating SAS is via modulation of body posture.
Takako Urabe, RN +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Scanning and resetting the phase of a pinned spiral wave using periodic far field pulses
New Journal of Physics, 2016 Spiral waves in cardiac tissue can pin to tissue heterogeneities and form stable pinned waves. These waves can be unpinned by electric stimuli applied close to the pinning center during the vulnerable window of the spiral. Using a phase transition curve (
T K Shajahan +4 more
doaj +1 more source
Moving people to deliver services : how can the WTO help? [PDF]
The previous General Agreement on Trade in Services (GATS) negotiations produced little liberalization of the movement of individual service providers (mode 4), and the potentially large global gains from suchmovement remain unrealized.
Chaudhuri, Sumanta +2 more
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