Results 81 to 90 of about 6,428,724 (313)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Offending White Men: Racial Vilification, Misrecognition, and Epistemic Injustice

Feminist Philosophy Quarterly, 2018
In this article I analyse two complaints of white vilification, which are increasingly occurring in Australia. I argue that, though the complainants (and white people generally) are not harmed by such racialized speech, the complainants in fact harm ...
Louise Richardson-Self
doaj   +1 more source

Self Study

, 2013
Department of Political Science Self Study Report for Academic Program ReviewDepartment of Political Science Self Study Report Academic Program ReviewDepartment of Political Science Self Study Report Academic Program ...
Academic Program Review, APR, Political Science, Self Study, Department of Political Science, Self Study Report   +2 more
core  

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Effect of Lateral Body Position on Heart Rate Variability in Patients with Sleep Apnea Syndrome

Journal of Arrhythmia, 2007
Sleep apnea syndrome (SAS) can exacerbate cardiovascular disease by augmenting activity of the sympathetic nervous system. One method of treating SAS is via modulation of body posture.
Takako Urabe, RN, Bonpei Takase, MD, Yumi Tomiyama, RN, Yumiko Maeda, RN, Yoshiko Ishikawa, RN, Hidemi Hattori, PhD, Akimi Uehata, MD, Masayuki Ishihara, PhD   +7 more
doaj   +1 more source

Perceptions of family functioning and self-concept in adolescent anorexia nervosa

, 2006
Authors have highlighted the importance of the family for the development of positive self-concept and identity, not only in mental health research but also in various developmental and social psychology fields.
Halse, Christine, Ha, My Trinh, Marsh, Herbert W., Martin, Andrew J.   +3 more
core  

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Vital Capacity and Selected Metabolic Diseases in Middle-Aged Japanese Men

Canadian Respiratory Journal, 2006
OBJECTIVE: To elucidate the association between vital capacity and the presence of selected metabolic diseases in middle-aged Japanese men.
Hidenari Sakuta, Takashi Suzuki, Hiroko Yyasuda, Teizo Ito   +3 more
doaj   +1 more source

Opening doors? Professional self-concept of pre-service teachers in relation to the inclusion of students with disabilities

, 2006
Current research indicates that a key to successful inclusive practices lies in teacher attitudes and preparation. It is proposed that effectively including students with disabilities in mainstream classrooms will be dependent on the focus and content of
Healey, Jean B., Marder, Kurt
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source