Results 71 to 80 of about 12,973,361 (304)

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Self-directed multimodal learning in higher education [PDF]

open access: yes, 2020
This book aims to provide an overview of theoretical and practical considerations in terms of self-directed multimodal learning within the university context.
Bailey, Roxanne   +9 more
core   +1 more source

A minimal mechanically consistent model of smoothly dividing disk-shaped cells

open access: yesnpj Systems Biology and Applications
Replication through cell division is one of the fundamental processes of life and a major driver of dynamics in systems ranging from bacterial colonies to embryogenesis, tissues and tumors.
Lukas Hupe   +5 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Persistent accelerations disentangle Lagrangian turbulence

open access: yesNature Communications, 2019
Particles in turbulence, as encountered in the atmosphere or the oceans, experience strongly varying local flow conditions over time. Bentkamp et al. show that this statistical complexity can be broken down into simpler parts, allowing for insights into ...
Lukas Bentkamp   +2 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Self-beliefs and bullying : unravelling the relation between bullying, being bullied and self-concept for upper elementary school aged children

open access: yes, 2006
Previous examinations of relations between bullying, victimisation, and self-concept have been flawed by erroneous research practices such as the un-attenuated use of dichotomous variables to measure relationships between continuous variables (Finger ...
Finger, Linda R.   +2 more
core  

Review of Ann Murray, ed. Germanistik in Ireland, Interrogating Normalcy

open access: yesForum, 2014
Germanistik in Ireland, Interrogating Normalcy, edited by Ann Murray, is a rich and diverse collection of essays from postgraduate students within German Studies.
Lizzy Robinson-Self
doaj   +3 more sources

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

The relation of self-concept to desirable educational outcomes

open access: yes, 2006
Reviewers (Byrne, 1996a, 1996b; Hattie, 1992; Marsh, Byrne, & Shavelson, 1988; Marsh & Craven, 1997; Craven, Marsh, & Burnett, 2003) consider that self-concept is multifaceted and espouse that self-concept cannot be adequately understood if its ...
Craven, Rhonda   +3 more
core  

Home - About - Disclaimer - Privacy