Results 61 to 70 of about 5,151,261 (292)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Prevalence of Oral Pain and Barriers to use of Emergency Oral Care Facilities Among Adult Tanzanians. [PDF]

, 2008
Oral pain has been the major cause of the attendances in the dental clinics in Tanzania. Some patients postpone seeing the dentist for as long as two to five days.
Ahadieli Raphael Senkoro, B Varenne, BH de Oliveira, C Miller, C Okunseri, Emil Namakuka Kikwilu, EP Macias, European Commission, Health and Consumer Protection Directorate – General Community Action Programme on Health Monitoring, Febronia Kokulengya Kahabuka, HJ Mosha, IM Matee, JM Wakiaga, Joyce Rose Masalu, JP Kessy, JT Johnson, K Zittel-Palamara, LB Käll, Ministry of Health, MK Ntabaye, N Ratnayake, RB Fillingim, VR Aggarwal, WH van Palenstein Helderman, World Health Organisation, Y Luo   +24 more
core   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Pain and Cognitive Concerns Among Breast Cancer Survivors: The Mediating Role of Substance Use Coping

Cancer Medicine
Context Bodily pain and cognitive concerns are both prevalent and share similar underlying mechanisms. A few studies have suggested that pain and cognitive concerns may be linked through substance use coping; however, this relationship remains unclear ...
Yesol Yang, Alai Tan, Leorey N. Saligan, Diane Von Ah   +3 more
doaj   +1 more source

FROM SELF-CARE TO COLLECTIVE CARE

Sur: International Journal on Human Rights, 2020
Human Rights Defenders (HRDs) across the world report a common experience of closing space for opposition to oppressive repositories of power, whether at the hand of government or the private sector. One of the strategies of resistance developed by HRDs
Lisa Chamberlain
doaj  

Explaining public satisfaction with health care systems: findings from a nationwide survey in China [PDF]

, 2015
Objective: To identify factors and covariates associated with health care system satisfaction in China. Context: Recent research suggests that socio-demographic characteristics, self-reported health, income and insurance, ideological beliefs, health ...
Duckett, Jane, Munro, Neil
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Drivers and barriers to promoting self-care in individuals living with multiple long-term health conditions: a cross-sectional online survey of health and care professionals

BMC Public Health
Background Self-care is an important part of preventing unwarranted decline in poor health linked to multimorbidity and in maintaining or improving health. Health and social care professionals provide support for self-care, which can positively influence
Susan Barber, Benedict Hayhoe, Sonia Richardson, John Norton, Manisha Karki, Austen El-Osta   +5 more
doaj   +1 more source

Implementation of Discharge Planning, Home Care, Knowledge Level And Independence In Mother Postpartum primiparous

Jurnal Riset Kesehatan, 2015
The objective of the study is to evaluate the levels of knowledge and self care in mothers with the primipara post partum in Purwokerto before and after intervention both control and experimental group.
Dina Indrati, Dyah Sulistyowati, Hartati Hartati, Ratifah Ratifah   +3 more
doaj   +1 more source