Results 81 to 90 of about 12,182,715 (399)

The Concept of "Self" and the "Other" in Western Movies [PDF]

open access: yes, 2001
Melodrama has been a part of the American life since colonial time. This genre, with its \u27hero-villain\u27 or \u27black and white\u27 development of characters, has formed the idea of the American heroes.
Basuki, R. (Ribut)
core   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Natal Family Disruptions and Lives in Non-Parental Care:Impacts on Children’s Emotional Health and Academic Success [PDF]

open access: yes, 2020
This research used a mixed methods design to evaluate the negative impacts of strains in children’s natal family environment, on their emotional and academic core self-concept, as well as how healthy non-parental relationships can help repair the damaged
Heid, Juliet
core   +1 more source

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

open access: yesMolecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo   +11 more
wiley   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Unemployment and Self-Concept

open access: yesEconomic Research-Ekonomska Istraživanja, 2013
AbstractThe article analyses the position of the unemployed in the labour market, primarily relationship between self-concept and self-esteem of workers and their motivation to seek work. The current crisis dramatically worsened labour market situation, making employment almost impossible for many, primarily the vulnerable groups (older, women). Survey
Redek, Tjaša   +2 more
openaire   +3 more sources

The Self-Concept Construction of Tattoo Users [PDF]

open access: yes, 2018
Basically tattoo which is on the body of tattoo users has their own meaning or a symbol that represents their feelings. The purpose of this study to explain and analyze the construction of self-concept tattoo users in Bandar Lampung.
Nugroho, H. (Heru)
core  

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

open access: yesMolecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li   +12 more
wiley   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

COMMUNICATION AND SELF-CONCEPT OF CHILDREN WITH DEAF AND SPEECH IMPAIRED

open access: yesJournal of Vocational Nursing, 2020
Introduction: The communication and interaction is the essence of every human as a social being. But, normal communications is not realyzed by the deaf speaking children.
Eko Mulyadi   +2 more
doaj   +1 more source

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