Results 51 to 60 of about 12,458,695 (229)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Role of Self Help Groups in Women Development- an Empirical Study

International Journal of Bio-Resource and Stress Management, 2011
SHGs enhance the equality of status of women as participants, decision-makers and beneficiaries in the democratic, economic, social and cultural spheres of life.
D. Amutha
doaj  

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Kinerja kelembagaan program sanitasi lingkungan berbasis masyarakat (SLBM)

Masyarakat, Kebudayaan dan Politik, 2016
SLBM Program implementation in Banyumas Regency involves many stakeholders, one of them is community. Through KSM, community has authority to manage program from, beside government roles as facilitator.
Denok Kurniasih, Paulus Israwan Setyoko, M Imron   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

The Influence of Online Self-Help Groups on Nutrition Management on the Nutritional Status of Cancer Patients Undergoing Chemotherapy

Indonesian Journal of Cancer
Background: Chemotherapy can result in toxicity that can affect the nutritional status of cancer patients. Symptoms that are side effects of chemotherapy include anorexia, changes in taste, nausea and vomiting, diarrhea, stomatitis, and constipation ...
Ririn Afrian Sulistyawati, Lalu Muhammad Panji Azali, Ari Pebru Nurlaily, Innez Karunia Mustikarani, Elok Faradisa, Muhammad Nur Rahmad   +5 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Beyond formation: Ensuring the sustainability of self-help groups

Social Sciences and Humanities Open
Self-help groups (SHGs) have mobilised rural women across India at scale; however, evidence regarding the factors that sustain these groups remains limited.
Tumelo Nigel Moyo, C. Paramasivam, Vedant Singh, Terence M. Mashingaidze   +3 more
doaj   +1 more source

Adoptive and foster families self-help groups as a tool for strengthening and empowering families

Socialinis Darbas: Patirtis ir Metodai, 2020
The article analyses the experience of foster families’ self-help groups in Lithuania in the context of the childcare system reform currently taking place in the country.
Lijana Gvaldaitė
doaj   +1 more source