Results 21 to 30 of about 2,851 (84)

Glial and Neuronal Neuroglian, Semaphorin-1a and Plexin A Regulate Morphological and Functional Differentiation of Drosophila Insulin-Producing Cells

Frontiers in Endocrinology, 2021
The insulin-producing cells (IPCs), a group of 14 neurons in the Drosophila brain, regulate numerous processes, including energy homeostasis, lifespan, stress response, fecundity, and various behaviors, such as foraging and sleep.
Jason Clements, Kurt Buhler, Mattias Winant, Veerle Vulsteke, Patrick Callaerts   +4 more
doaj   +1 more source

O SUFIXO –INHO NA FALA DE ITAÚNA (MG): UM ESTUDO LÉXICO-SEMÂNTICO

Pensar Acadêmico, 2019
O objetivo deste artigo é analisar itens lexicais nos quais aparece o sufixo –inho. Nessa análise, o foco recai sobre os possíveis valores semânticos que podem ser aferidos desse sufixo; e, adicionalmente, se os sentidos que dele são depreendidos estabelecem correlação com a base lexical no qual se conectam.
openaire   +2 more sources

Lentiviral Mediated Expression of Soluble Neuropilin 1 Inhibits Semaphorin 3A-mediated Collapse Activity in Vitro

Basic and Clinical Neuroscience, 2021
Introduction: Semaphorin 3A (Sema 3A) is a secreted protein, which plays an integral part in developing the nervous system. It has collapse activity on the growth cone of dorsal root ganglia.
Keivan Nedaei, Mahdi Hesaraki, Saeideh Mazloomzadeh, Mehdi Totonchi, Ali Reza Biglari   +4 more
doaj  

Semaphorin-1a prevents Drosophila olfactory projection neuron dendrites from mis-targeting into select antennal lobe regions. [PDF]

PLoS Genetics, 2017
Elucidating how appropriate neurite patterns are generated in neurons of the olfactory system is crucial for comprehending the construction of the olfactory map.
Hung-Chang Shen, Sao-Yu Chu, Tsai-Chi Hsu, Chun-Han Wang, I-Ya Lin, Hung-Hsiang Yu   +5 more
doaj   +1 more source

O VALOR CAUSATIVO DO PREFIXO [DES-]: UM ESTUDO LÉXICO-SEMÂNTICO

Pensar Acadêmico, 2017
O objetivo desta pesquisa é proceder à análise do prefixo [des-], segundo as acepções semânticas que podem ser refletidas nesse morfema. Pretende-se investigar os predicados que figuram com esse prefixo, delineando os valores semânticos específicos atribuídos à base lexical com a qual se conecta. Adicionalmente, implementamos o sentido “causativo” que [
openaire   +1 more source

Identifying a Csmd3+ Microglial Subpopulation that Drives Cold‐to‐Hot Transition and Immune‐Cure in Glioblastoma

Advanced Science, EarlyView.
The study establishes an immune‐cure (ICu) mouse model based on a TMEMed G422TN‐GBM system that faithfully recapitulates human TMEMed GBM. scRNA‐seq analysis reveals a Csmd3+ microglial subset with innate immune memory (IIM) potential that potently suppresses GBM growth, drives a TME cold‐to‐hot transition, and induces 100% ICu in long‐term survival ...
Hai‐Feng Jiang, Pan‐Pan Gao, Yu‐Wen Du, Li‐Qin Wu, En‐Zhi Yin, Qi An, Ze‐Hua Ding, Jin‐Wen Shi, Ya Shu, Ruoqiao Chen, Feng Liu, Mingfeng Li, Xiao Qian Chen   +12 more
wiley   +1 more source

Regulation of semaphorin 4D expression and cell proliferation of ovarian cancer by ERalpha and ERbeta

Brazilian Journal of Medical and Biological Research
Ovarian cancer is one of the most common malignancies in women. Semaphorin 4D (sema 4D) is involved in the progress of multiple cancers. In the presence of estrogen-like ligands, estrogen receptors (ERα and ERβ) participate in the progress of breast and ...
Y. Liu, Y. Hou, L. Ma, C. Sun, J. Pan, Y. Yang, H. Zhou, J. Zhang   +7 more
doaj   +1 more source

Single‐cell atlas of neuroglial dynamics in SNCA‐A53T Parkinson's disease mouse model

Animal Models and Experimental Medicine, EarlyView.
We performed single‐cell RNA sequencing of midbrain and striatal tissues from SNCA‐A53T Parkinson's disease (PD) mice, revealing glia‐enriched PD‐risk gene signatures and disease‐specific subpopulations. Transcriptional dysregulation of key TFs (e.g., Rorb, Foxc1) and enhanced neuroinflammatory signaling (SEMA, CCL, MIF) were identified.
Binqing Qin, Zichu Fu, Xuanxuan Zou, Senmao Chai, Jingjing Weng, Puqing Wang, Xiaodong Sun, Ming Sang   +7 more
wiley   +1 more source

Implementasi Surat Edaran Mahkamah Agung Nomor 4 Tahun 2016 pada Putusan Hakim dalam Pemberian Perlindungan Hukum bagi Pembeli Beritikad Baik

Jurnal Konstitusi, 2019
Dalam melindungi pihak yang beritikad baik dalam suatu perjanjian maka dibutuhkan peraturan yang dapat memberikan kepastian hukum. Pada tahun 2016 Mahkamah Agung melakukan rapat pleno dan menerbitkan Surat Edaran Mahkamah Agung (SEMA) Nomor 4 Tahun 2016,
Fadhila Restyana Larasati, Mochammad Bakri   +1 more
doaj   +1 more source

Gonadal development in scorpion mud‐turtles, Kinosternon scorpioides, in a controlled environment

The Anatomical Record, EarlyView.
Stage 20 was identified as the critical point for gonadal differentiation in Kinosternon scorpioides, providing key insights into sex determination. These findings enhance conservation strategies by supporting reproductive management and population viability in both in situ and ex situ programs. Abstract Research on gonadal development including sexual
Brenda Braga, Verônica Oliveira‐Bahia, Maria Auxiliadora Ferreira, José Ribamar Felipe Marques, Diva Araújo Guimarães   +4 more
wiley   +1 more source