Results 41 to 50 of about 12,689 (172)

Semaglutide normalizes increased cardiomyocyte calcium transients in a rat model of high fat diet‐induced obesity

ESC Heart Failure, Volume 12, Issue 2, Page 1386-1397, April 2025.
Sequeira et al. reveal how the glucagon‐like peptide‐1 receptor agonist (GLP‐1‐RA) semaglutide restores cardiomyocyte function in rats subjected to a high‐fat/high‐fructose diet (HFD). Employing fluorescence‐ and patch‐clamp technology in isolated cardiac myocytes, they demonstrate that semaglutide reverses HFD‐induced activation of L‐type calcium ...
Vasco Sequeira, Julia Theisen, Katharina J. Ermer, Marie Oertel, Anton Xu, David Weissman, Katharina Ecker, Jan Dudek, Martin Fassnacht, Alexander Nickel, Michael Kohlhaas, Christoph Maack, Ulrich Dischinger   +12 more
wiley   +1 more source

Birlikte Sema Uygulaması Üzerine Frankfurt Okulu Ekseninde Eleştirel Bir Değerlendirme

Medya ve Din Araştırmaları Dergisi
Çalışma Mevlevîlik tarikatının tarihsel süreci ile birlikte sema ritüelinin dönüşümünü ve birlikte semâ uygulamasını ele almaktadır. Mevlevîlik, 13. yüzyılda Sultan Veled tarafından kurulan ve Osmanlı’dan Cumhuriyet’e geçiş sürecinde önemli değişimlere ...
Zehra Öğüt
doaj   +1 more source

Wedelolactone enhances osteoblastogenesis but inhibits osteoclastogenesis through Sema3A/NRP1/PlexinA1 pathway

Frontiers in Pharmacology, 2016
Bone remodeling balance is maintained by tight coupling of osteoblast-mediated bone formation and osteoclast-mediated bone resorption. Thus, agents with the capacity to regulate osteoblastogenesis and osteoclastogenesis have been investigated for therapy
Yanqiu Liu, Xiao fei Han, Jun xia Bo, Hui peng Ma   +3 more
doaj   +1 more source

c‐Met‐Targeted Imaging Agents: Progress and Challenges

iRADIOLOGY, EarlyView.
This review summarizes recent advances in c‐Met‐targeted imaging probes, including hepatocyte growth factor (HGF) ligands, antibodies, peptides, and small molecules across magnetic resonance imaging (MRI), positron emission tomography (PET), single‐photon emission computed tomography (SPECT), and optical imaging modalities.
Yonghao Li, Aiyan Ji, Qihang Ding, Hongyue Lou, Zhen Cheng   +4 more
wiley   +1 more source

Adherence and treatment discontinuation of oral semaglutide and once‐weekly semaglutide injection at 12 month follow‐up: Japanese real‐world data

Journal of Diabetes Investigation
Adherence and treatment continuation rates of the glucagon‐like peptide‐1 receptor agonist (GLP‐1RA) semaglutide for both oral (O‐SEMA) and subcutaneous injection (SEMA‐SC) remain unknown in real‐world clinical practice.
Takeshi Horii, Chikako Masudo, Yui Takayanagi, Yoichi Oikawa, Akira Shimada, Kiyoshi Mihara   +5 more
doaj   +1 more source

O SUFIXO –INHO NA FALA DE ITAÚNA (MG): UM ESTUDO LÉXICO-SEMÂNTICO

Pensar Acadêmico, 2019
O objetivo deste artigo é analisar itens lexicais nos quais aparece o sufixo –inho. Nessa análise, o foco recai sobre os possíveis valores semânticos que podem ser aferidos desse sufixo; e, adicionalmente, se os sentidos que dele são depreendidos estabelecem correlação com a base lexical no qual se conectam.
openaire   +2 more sources

Preclinical Toxicity Screening of Sodium Dodecanoyloxybenzenesulfonate (LOBS) as a New Alternative Biocide Using In Vitro and In Vivo Models

Environmental Toxicology, EarlyView.
ABSTRACT Sodium hypochlorite is a well‐established biocide extensively used in both living and industrial environments; however, exposure to it or improper handling can harm the human body and the environment. Thus, safer alternatives to sodium hypochlorite are required.
Seung Eui Min, Seunghee Oh, Min Seong Jang, Kang‐Hyun Han   +3 more
wiley   +1 more source

DİN-SANAT İLİŞKİSİ VE BUNUN SOMUT BİR YANSIMASI OLARAK MEVLEVÎ SEMÂ ÂYİNİ

, 2009
Bu çalışmanın amacı, genel anlamda din-sanat ilişkisini ve bunun somut bir yansıması olarak Mevlevî Semâ Âyini’ni incelemektir. Çalışmada, ilk olarak din-sanat ilişkisi ele alınmakta ve sembolik unsurların sanat ve din için taşıdığı önem incelenmektedir.
Hüsnü Aydeniz
core   +1 more source

Kekuatan Hukum Mengikat SEMA No. 7 Tahun 2014 tentang Pengajuan Permohonan Peninjauan Kembali dalam Perkara Pidana

Kanun, 2017
ABSTRAK: Pada tataran praktik, SEMA No. 7 Tahun 2014 yang menyatakan pengajuan Peninjauan Kembali hanya boleh satu kali mengesampingkan Putusan MK No. 34/PUU-XI/2013 yang membatalkan Pasal 268 ayat (3) KUHAP yang menyatakan pengajuan Peninjauan Kembali ...
Riki Yuniagara, Eddy Purnama, M. Saleh Sjafei   +2 more
doaj   +1 more source

Reduced-Frequency GLP1 Therapy Maintains Weight, Body Composition, and Metabolic Syndrome Improvements: A Case Series. [PDF]

Obesity (Silver Spring)
ABSTRACT Objective This study aimed to evaluate whether reduced‐frequency dosing of GLP1 receptor agonists maintains weight loss, body composition, and metabolic syndrome improvements following successful initial treatment with standard weekly therapy. Methods This retrospective case series included 30 adults who achieved weight plateau while on weekly
Wong M, Wu A, Garhe PK, Biermann M.
europepmc   +2 more sources