The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Durante uma ação performática realizada para a câmera de vídeo, sigo um espelho em movimento e aponto uma arma para o meu reflexo, criando assim uma perseguição à minha imagem. Os trabalhos que atualmente estou desenvolvendo fazem parte da pesquisa sobre imagens em movimento e artes visuais, com ênfase nos suportes (de projeção de imagens e suporte ...
openaire +3 more sources
Delay versus Stickiness Violation Trade-offs for Load Balancing in Large-Scale Data Centers
Most load balancing techniques implemented in current data centers tend to rely on a mapping from packets to server IP addresses through a hash value calculated from the flow five-tuple.
Borst, Sem, Liang, Qingkai
core +1 more source
Assessment of FEMA356 nonlinear static procedure and modal pushover analysis for seismic evaluation of buildings [PDF]
Nonlinear static analysis as an essential part of performance based design is now widely used especially at design offices because of its simplicity and ability to predict seismic demands on inelastic response of buildings.
Khoshnoud, Hamid Reza +1 more
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Cinema Sem Conflitos. Quando Através do Cinema Também se Pode Mediar Conflitos em Contexto Escolar
O presente artigo aborda o desenvolvimento de um projeto na área da Educação em Portugal e que compreende uma dupla vertente, teórico-prática, e onde é proposta a criação e a implementação de um Recurso Educacional Aberto – designado Cinema Sem ...
Ricardo Braga Silva +2 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Following the introduction of Buddhism to China, various strategies of accommodation with Chinese culture were developed, all amounting to some form of syncretism with Chinese religions, mainly Confucianism. Buddhism in pre-modern Korea displayed similar
Sem Vermeersch
doaj +1 more source
Microscopic Insight to Nonlinear Voltage Dependence of Charge in Carbon-Ionic Liquid Supercapacitors
The impact of cell voltage on the capacitance of practical electrochemical supercapacitors is a phenomenon observed experimentally, which lacks a solid theoretical explanation. Herein, we provide combined experimental and molecular dynamics investigation
Aleksandar Y. Mehandzhiyski +4 more
doaj +1 more source

