Results 51 to 60 of about 5,354,089 (273)
Om framstillinga av sørsamar i Trøndelags historie
Heimen, 2017 On the depiction of the South Saami people in Trøndelags historie The 2005 publication of a three-volume history of the Trøndelag region ignited a heated debate.
Leiv Sem
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Modelling rural labor: an application to São Paulo, Brazil
Economia Aplicada, 2002 The question of modelling rural labor is discussed and a seemingly unrelated regressions (SUR) model is suggested. An application is presented analyzing three labor categories in the State of São Paulo, Brazil; farmer' s family workers, permanent ...
Francisco Alberto Pino +3 more
doaj
SEM-EDS analyses of small craters in stardust aluminium foils: implications for the Wild-2 dust distribution [PDF]
, 2007 Implications for the Wild-2 dust distribution of the statistical results obtained by SEM-EDS from nearly 300 impact craters on aluminium foils of the Stardust sample tray ...
Borg, J. +15 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Ensaios de Geografia, 2023 Este trabalho busca apresentar, por meio de imagens e mapas, os impactos da mineração de salgema no município de Maceió, capital do Estado de Alagoas. Por mais de 30 anos a extração mineral aconteceu de maneira concomitante com o crescimento urbano.
openaire +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source